Gastric Cancer: From New Molecular Insights to Innovative Robotical Approaches
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 13661
Special Issue Editors
Interests: cancer genetics; gastric cancer; angiogenesis; tumor metabolism; CRISPR gene editing
Special Issues, Collections and Topics in MDPI journals
Interests: oncology; gastric surgery; robotics; new technologies; minimally invasive surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastric cancer is to date the fifth most common malignancy worldwide, accounting for a third of all cancer-related deaths, and, even though huge research efforts have been spent to better understand such disease, it is urgent to challenge this kind of cancer from different points of view.
This Special Issue aims to collect all new molecular evidences focusing on the heterogeneous biology of gastric cancer, especially evaluating the genetic and prognostic discrepancies between Asian and Caucasian populations. Helicobacter pylori infection, lifestyle, and diet habits are well established gastric cancer risk factors, but still remain to be defined if any different genetic cause is in relationship between the divergent clinical presentation between Eastern and Western populations. It is in fact well known that gastric cancer in Eastern countries is always diagnosed at earlier stages than in Western ones. Such discordances reflect not only a probable different molecular behavior but also diffent clinical approaches. The possibility to better define gastric cancer genetics differences plays a pivotal role, as it can lead to earlier stage diagnosis and to higher possibility of minimally invasive tratments such as robotic surgery.
In this context, innovative approaches such as the generation of knockout cell lines via CRISPR will fuel the research of hidden molecular mechanisms. Moreover, we intend to analyze the studies revealing new insights about chemoresistance, which is still the main challenge to face. We also want to explore all the brand new therapeutic options regarding chemotherapy and surgical approaches.
We do believe that the articles included in this Special Issue will be helpful to provide an overview of the current knowledge about gastric cancer and will inspire new advancement in basic and translational cancer biology.
Dr. Alessio Biagioni
Dr. Fabio Staderini
Guest Editors
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Keywords
- Gastric Cancer
- Cancer Biomarkers
- Cancer Genetics
- Tumor Angiogenesis
- Chemotherapies
- Drug Resistance
- Robotic Surgery
- Molecular Biology
- CRISPR
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