RNA Biology and mRNA in Diseases

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 116

Special Issue Editor

College of Life and Health Sciences, Northeastern University, Shenyang 110167, China
Interests: embryo development; genome editing; epigenetics; cancer; stem cells; somatic cell nuclear transfer; oxidative stress; pig; natural products; phase separation

Special Issue Information

Dear Colleagues,

The understanding of RNA biology and the development of mRNA-based therapeutics have significantly advanced the field of disease treatment, offering promising solutions for a wide range of medical conditions. This Special Issue aims to gather pioneering research on the mechanisms of RNA regulation and the innovative applications of mRNA therapeutics in disease management. We encourage submissions that investigate the synthesis, transportation, modification, translation, and decoy degradation of RNA and explore the design, synthesis, and delivery of mRNA-based vaccines and drugs, as well as their applications in treating diseases such as cancer, infectious diseases, and genetic disorders. We are particularly interested in studies that demonstrate the novel approach to enhance the efficacy of mRNA-based therapeutics in animal or laboratory settings, including those reporting on gene expression, immune responses, and therapeutic outcomes. We invite original research articles and comprehensive reviews that focus on, but are not limited to, stress granules, RNA fate, RNA-based vaccines, targeted mRNA delivery systems, and the latest advancements in RNA technology, such as CRISPR/Cas13, RNA labels, and biosensors. This Special Issue aims to provide a platform for researchers to share their findings and contribute to the growing body of knowledge in RNA biology and mRNA-based therapeutics.

Dr. Yongye Huang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stress granule
  • cRISPR/Cas13
  • vaccine
  • mRNA drug
  • antisense oligonucleotides
  • RNA methylation
  • microRNA
  • long non-coding RNA
  • RNA binding
  • RNA activation
  • circular RNA
  • fluorescent RNA
  • cell surface RNA
  • cancer
  • neurodegenerative disease

Published Papers

This special issue is now open for submission.
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