Biosynthesis of Ribosomes
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 246
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biosynthesis of ribosomes is a fundamental process essential for cell growth and proliferation, involving the precise assembly of ribosomal RNA (rRNA) and proteins. Despite its centrality to cellular function, many aspects of ribosome biosynthesis remain incompletely understood. In recent years, the molecular details of this complex process have become increasingly clear, allowing for the definition of the specific roles of most ribosomal components and ribosome-assembly factors. Moreover, it is now evident that specific alterations in ribosome biogenesis in humans can play a major causative role in several severe disorders, ranging from rare inherited syndromes to various cancers. This Special Issue of Biology aims to gather cutting-edge research on the molecular mechanisms governing ribosome biosynthesis. We welcome submissions that investigate the transcription, processing, and modification of rRNA, the synthesis and folding of ribosomal proteins, and the dynamic assembly of these components into functional ribosomes. We welcome any contributions, both primary research studies and literature reviews, which address the dynamic and molecular mechanism of ribosomal subunit assembly, the regulation of ribosome biogenesis in response to cellular signals, and the consequences of its dysregulation in diseases such as cancer and ribosomopathies. This Special Issue aims to provide a comprehensive overview of current advances in ribosome biosynthesis and to stimulate further research in this pivotal area of cell biology.
Dr. Fuxing Zeng
Guest Editor
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Keywords
- ribosome biogenesis
- ribosome assembly
- ribosome precursor
- rRNA modification
- ribosomal proteins
- ribosomopathies
- assembly factors
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