Roles and Use of Extracellular Vesicles in Health and Disease
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: closed (15 May 2023) | Viewed by 14209
Special Issue Editors
Interests: proteomics; biomarkers; blood brain barrier; Alzheimer’s disease
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles released by a variety of cells into the extracellular microenvironment. EVs represent a mechanism of cell-to-cell communication through the direct stimulation of cells via receptor-mediated contact and/or through the transfer of genetic material (DNA, RNAs), proteins, and lipids. EVs display versatile physiological functions and are involved in the regulation of main routes of signaling and intercellular information transfer between different cell types, possibly even cross-kingdom. However, EVs are also key players in various pathological functions and are involved in many diseases, including inflammation, cancer, diabetes, cardiovascular and cerberovascular diseases, autoimmune diseases, renal failure, and many disorders of the central nervous system. EVs are also excellent candidates as a source of biomarkers in these diseases as their cargoes reflect the pathophysiological signatures of the cell of origin. Finally, EVs are attracting much interest as a platform for therapeutic development in many diseases.
The purpose of this Special Issue is to convey current understanding about extracellular vesicles (EVs) and their role in health and disease, as well as to investigate recent advancements in the field and provide an overview of EVs' usage as therapeutic delivery vehicles in various diseases. Original review and research articles are welcome.
Dr. Arsalan Haqqani
Dr. Amanpreet Badhwar
Guest Editors
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Keywords
- extracellular vesicles (EVs)
- cellular biology
- inflammation
- diseases
- biomarkers
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