Probiotics and Gut Microbiome-Prospects and Challenges

Dear Colleagues,

The human gut harbors a complex and dynamic microbial ecosystem, known as the gut microbiome, which plays a crucial role in maintaining host health. The gut microbiome is involved in various physiological processes, including digestion, nutrient absorption, immune modulation, and protection against pathogens. Dysbiosis in the composition and function of the gut microbiome, has been associated with numerous diseases, such as inflammatory bowel disease, obesity, diabetes, and neurological disorders. Probiotics have emerged as a promising approach to modulate the gut microbiome and promote host health. Recent advances in probiotic research have shed light on the diverse mechanisms by which probiotics exert their beneficial effects, including the production of antimicrobial compounds, the modulation of immune responses, and the regulation of gut barrier function. However, the development and application of probiotics also face significant challenges, such as the need for better characterization of beneficial mechanisms and probiotic strains, the optimization of probiotic formulations and delivery systems, and the establishment of appropriate regulatory frameworks. This Special Issue aims to provide a comprehensive overview of the current state of knowledge in the field of probiotics and the gut microbiome, highlighting the latest research findings, identifying key challenges and opportunities, and discussing future directions for the development of safe and effective probiotic interventions to promote human health. Understanding the complex interactions between probiotics and the gut microbiome is crucial for harnessing their potential in preventing and treating various diseases, and for developing personalized probiotic therapies tailored to individual needs.

We are pleased to invite you to contribute to the Special Issue “Probiotics and Gut Microbiome-Prospects and Challenges” in the Microbiology section of the Journal: Biology. This Special Issue aims to provide a comprehensive overview of the current state of knowledge in the field of probiotics and the gut microbiome, highlighting the latest research findings, identifying key challenges and opportunities, and discussing future directions for the development of safe and effective probiotic interventions to promote human health.

By covering a wide range of topics related to probiotics and the gut microbiome, including the development and characterization of novel probiotic strains, the mechanisms of action of probiotics, the potential applications of probiotics in preventing and treating various diseases, and the challenges associated with the formulation, delivery, and regulation of probiotic products, this Special Issue will provide a valuable resource for researchers, clinicians, and industry professionals working in the field.

Dr. Jiye Cheng
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• probiotics
• gut microbiome
• microbiota
• gut health
• probiotic mechanisms
• probiotic applications
• probiotic challenges
• probiotic formulation
• probiotic delivery
• microbiome-host interactions