Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 3308
Special Issue Editor
Interests: neurodegenerative disease; addiction; microscopy; senescence; therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are lipid-bound vesicles secreted by cells into the extracellular space. The three main subtypes of EVs—microvesicles, exosomes, and apoptotic bodies—are differentiated based on their biogenesis, release pathway, size, content, and function. The content or “cargo” of EVs include nucleic acids, lipids, proteins, and metabolites. The role of EVs in cell–cell communication and their ability to act as carriers of biomarkers for diseases are now well established. EVs are widely considered promising therapeutic options as they have a long circulating half-life, are well tolerated by the human body, are capable of penetrating cell membranes and targeting specific cell types, and have the capacity to be engineered. Indeed, the use of EVs (predominantly exosomes) as therapeutic agents and/or drug delivery systems in neurodegenerative diseases, cancers, stroke, myocardial infarction, and several other pathologies has been the subject of intense research. Despite recent advances, a better understanding of the mechanisms by which EVs function would help unlock the full potential of EV-based therapeutics. This Special Issue welcomes articles focused on the use of EVs, including exosomes, as therapeutic agents, with a focus on articles that provide a better understanding of the uptake, biodistribution, and trafficking of EVs or elucidate the mechanisms by which EVs exert their therapeutic effects.
Dr. David J. Rademacher
Guest Editor
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Keywords
- extracellular vesicles
- exosomes
- therapeutics
- drug delivery
- bioengineering
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Related Special Issue
- Extracellular Vesicles and Exosomes as Therapeutic Agents in Biomedicines (11 articles)
