Cerebral Hemorrhages: From Pathophysiologic Mechanisms to Therapeutic Strategies
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 4605
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cerebral hemorrhages are a group of diseases (intracerebral hemorrhage, intraventricular hemorrhage, subarachnoid hemorrhage, etc.) that induce brain damage and subsequent functional impairment. Brain edema, vasospasm, breakdown of the blood‒brain barrier, activation of microglia/macrophages, and remodeling of the perilesional environment are major pathological substrates in hemorrhagic stroke. A wide variety of conditions, risk factors, and disorders (such as hypertension, aneurysm, tumor, trauma, arteriovenous malformation, moyamoya disease, etc.) lead to cerebral hemorrhages, although the underlying pathophysiologic mechanisms remain unclear and effective treatments are limited.
This Special Issue, titled “Cerebral hemorrhages: From Pathophysiologic Mechanisms to Therapeutic Strategies”, focuses on the pathophysiologic mechanisms of primary and secondary brain injury, the mechanism of aging and sex differences, mechanisms of impaired blood‒cerebrospinal fluid barriers, and perilesional environment remodeling leading to immune cells infiltration and microbleeds. This Special Issue also welcomes articles that provide an overview of the role of white matter injury, phagocytosis, hemolysis, and immune system molecular mechanisms in the pathogenesis of cerebral hemorrhage diseases and corresponding treatment approaches. As such, this Special Issue welcomes submissions of original research and review articles related to any aspect of the pathophysiologic mechanisms and therapeutic strategies of hemorrhagic stroke diseases.
Dr. Yingfeng Wan
Guest Editor
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Keywords
- hemorrhagic stroke
- white matter injury
- brain blood barrier
- phagocytosis
- hemolysis
- immune cells
- aging
- sex difference
- vasospasm
- blood‒cerebrospinal fluid barrier
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