Recent Advances in Traumatic Brain Injury Using Large Animal Models
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Biomedical Engineering and Materials".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 460
Special Issue Editors
Interests: traumatic brain injury; ventilator-induced lung injury; concussion; large animal models; swine; biomarkers; biomechanics
Special Issue Information
Dear Colleagues,
Traumatic brain injury is a paramount global health concern and presents a substantial economic burden worldwide. Detecting mild traumatic brain injury (mTBI), which constitutes the majority of TBI cases, poses challenges as brain abnormalities are not easily detected using conventional diagnostic imaging, despite cognitive dysfunction and prolonged impairment. From a physiological perspective, acute primary brain injury is believed to stem from tissue deformation caused by the inertial movement of the brain following rapid head rotation. In order to comprehend the mechanisms and pathophysiology of mTBI, large animal models are a valuable tool for studying the biomechanics of TBI as neuroanatomical characteristics, such as white and grey matter distinctions in addition to well-circumscribed gyri and sulci, appropriate the effects of mechanical loading on the brain.
This Special Issue will serve to address a preclinical platform for developing and evaluating diagnostic as well as prognostic tools and interventions through the presentation of original research articles, reviews, and rapid short communication papers focusing on "Recent Advances in Traumatic Brain Injury Using Large Animal Models". The primary target audience for this Special Issue includes researchers employing an integrated biomechanics approach that incorporates large animal models, cell and tissue experiments, human studies, and the subsequent translation of these findings into preclinical therapeutic trials aimed at mitigating and preventing brain injuries.
Prof. Dr. Susan Margulies
Dr. Anna Oeur
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- traumatic brain injury
- large animal models
- biomarkers
- experimental
- neurotrauma
- neurological disorders
- biomechanics
