Molecular Biomarkers in Inflammatory Bowel Disease: Pathophysiology and New Therapeutic Strategies—Second Edition
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 1164
Special Issue Editor
Interests: inflammatory bowel disease; biomarkers; pathophysiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammatory bowel disease (IBD) is a comprehensive medical term that represents a spectrum of chronic, idiopathic, and immunologically mediated digestive tract disorders, with the main representatives being Crohn’s disease and ulcerative colitis. Although there are still many unknown factors regarding the etiology and pathophysiology of this disease, it is believed to involve a complex interplay between genetic, epithelial, environmental, microbial, and immunological factors.
Considering that the number of affected patients is increasing worldwide and overall disease management often requires complex and expensive testing, there is a need for convenient, non-invasive, and economical solutions. It is becoming clear that molecular biomarkers are starting to represent a key component in IBD studies, as they can fulfil our requirements and potentially improve numerous areas in IBD management, including timely diagnosis, treatment response, the monitoring of disease activity, and mucosal healing. However, as the current most widely used biomarkers in IBD have certain shortcomings, there is substantial room for improvement and new studies in this field.
Therefore, the main goal of the upcoming Special Issue is to feature the most comprehensive and up-to‑date original research and specialized reviews helping to encompass and improve knowledge regarding molecular biomarkers that play significant roles in the complex pathophysiological pathways of IBD development, as well as exploring their potential to become new, effective, and reliable tools in disease monitoring, treatment strategies, and precision medicine.
Dr. Marino Vilović
Guest Editor
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Keywords
- inflammatory bowel disease (IBD)
- Crohn’s disease
- ulcerative colitis
- biomarkers
- molecular biomarkers in IBD
- pathophysiology
- therapeutic approaches in IBD
- precision medicine
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