Pharmacokinetics of Biomedicines: Impact on Pre-clinical Development and Clinical Use 2nd Edition
A special issue of Biomedicines (ISSN 2227-9059).
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1646
Special Issue Editor
Interests: pharmacokinetics; pharmacogenetics; pharmacometabolomics; clinical and pre-clinical development; drug monitoring therapy; drug disposition; bioanalytical assays; immunogenicity; tailored dosing; precision medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We thank all the authors who took part in preparing the first edition of this Special Issue.
In the second edition of the Special Issue “Pharmacokinetics of Biomedicine: Impact on Pre-clinical Development and Clinical Application”, the main focus is on the pharmacokinetics and pharmacogenetics of new and well-known medicines, their characteristics when used in monotherapy and polytherapy for a wide range of diseases in children, adolescents, and adults. Significant attention will also be paid to the study of medicine pharmacokinetics at pre-clinical development and clinical use stages.
Chemical, pre-clinical developments, and clinical application are the main problems for many medicines due to their different physico-chemical properties and possible drug–drug interactions. Pharmacogenetics can explain the much more complex pharmacokinetic behavior of medicines in various patients, which strongly influences the strategy of their pre-clinical testing and clinical use, including strategies for clinical, pharmacokinetic, and pharmacogenetic monitoring, and the personalization of pharmacotherapy. In addition, the pharmacokinetic profile, as well as pharmacodynamics and toxicity, can be influenced by specific factors, such as immunogenicity; they are often regulated by different procedures, and, because of their unique properties, various types of bioanalytic analyses are needed for their effective quantification: mass analysis, activity analysis, and immunogenicity analysis.
We invite authors to submit original studies and reviews that highlight the factors specific to a particular medicine(s) and/or a particular patient that affect the pharmacokinetic behavior of a wide range of drugs, and that must be taken into account for successful pharmacotherapy in real clinical practice.
Dr. Natalia Shnayder
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmacokinetics
- pharmacogenetics
- pharmacometabolomics
- clinical and pre-clinical development
- drug monitoring therapy
- drug disposition
- bioanalytical assays
- immunogenicity
- tailored dosing
- precision medicine
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
