Immunogenetic Regulations for Disease Prognosis

Dear Colleagues,

Gaining insight into immunogenetic regulations is critical to further our understanding of the operation of the immune system at the molecular and cellular levels, devise personalized medicine strategies, and develop vaccines and therapies that are more efficacious against a wide range of immune-related ailments. Immune-related genes, population diversity and the environment may influence the disease susceptibility and immune responses through cytokines, receptors and additional components of the immune system. To reduce drug immunogenicity in emerging infectious, chronic and lifestyle diseases, and to understand host–pathogen interactions, it is important to understand the immune evasion and survival strategies of pathogens, host susceptibility, epigenetic regulators, modulators and inflammation.

Immunogenetics is useful for understanding of the basic mechanisms involved in diagnosis, therapeutics, immune tolerance, immune surveillance, major innate immune cell types, such as macrophages and neutrophils, and adaptive immune cell types, such as T lymphocytes and B lymphocytes, as well as the lymphatic system in disease conditions. For the anatomical, physiological, physiological, environmental and epidemiological statistical studies covered in this issue, contributions to knowledge of the genetic and epigenetic factors affecting immunity, intraspecific diversity, inheritance of tissue antigen and tissue compatibility through molecular-, cellular- and organ-level studies are welcome. This Special Issue features contributions to the field that enable in-depth research on drug effects and the mechanisms underlying disease progression, including advances in clinical biomarkers, regenerative medicine, microscopic techniques, heterologous gene expression, organ transplantation and multi-omics profiles. This Special Issue focuses on immune systems and their relationships to innovation, emerging technologies, natural medicine and the environment in order to present conceptual and practical advances regarding the state-of-the-art research on molecular and cellular mechanism. In order to create methods for early disease detection, real-time monitoring and prevention, it is intended to promote interest and research in this fascinating area.

Dr. Anshuman Mishra
Dr. Trim Lajqi
Guest Editors

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• immunity
• host susceptibility
• gene expression
• biotechnology
• disease resistance
• immunogenicity
• drug monitoring
• vaccines
• adaptive immunity