You are currently viewing a new version of our website. To view the old version click .

Biomedicines, Volume 13, Issue 10

October 2025 - 256 articles

Cover Story: Peanut and tree nut allergies are among the leading causes of severe allergic reactions in childhood, often developing early in life. This review examines the complex interplay of genetic, immunologic, and environmental factors underlying IgE-mediated sensitization, with particular emphasis on the critical role of skin barrier dysfunction. It summarizes advances in prevention—especially early peanut introduction and barrier-supporting interventions—and explores emerging diagnostic and therapeutic strategies, including molecular biomarkers and immunotherapy. By elucidating early immune and molecular signatures, this review highlights prospects for targeted prevention and improved management of nut allergy in children. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (256)

  • Article
  • Open Access
393 Views
16 Pages

Background: The human acellular amniotic membrane (HAAM) is widely used as a decellularized bioscaffold in tissue engineering to promote wound healing, but its clinical application is limited by poor mechanical properties, rapid degradation, and hand...

  • Article
  • Open Access
428 Views
21 Pages

Beyond Biomarkers: Blending Copeptin and Clinical Cues to Distinguish Central Diabetes Insipidus from Primary Polydipsia in Children

  • Diana-Andreea Ciortea,
  • Carmen Loredana Petrea (Cliveți),
  • Gabriela Isabela Verga (Răuță),
  • Sorin Ion Berbece,
  • Gabriela Gurău,
  • Silvia Fotea and
  • Mădălina Nicoleta Matei

Background: Polyuria–polydipsia syndrome (PPS) in children poses a major diagnostic challenge, as central diabetes insipidus (CDI) and primary polydipsia (PP) require distinct treatments. Although copeptin is a robust diagnostic biomarker, usin...

  • Article
  • Open Access
503 Views
21 Pages

Brain Tumor Classification in MRI Scans Using Edge Computing and a Shallow Attention-Guided CNN

  • Niraj Anil Babar,
  • Junayd Lateef,
  • ShahNawaz Syed,
  • Julia Dietlmeier,
  • Noel E. O’Connor,
  • Gregory B. Raupp and
  • Andreas Spanias

Background/Objectives: Brain tumors arise from abnormal, uncontrolled cell growth due to changes in the DNA. Magnetic Resonance Imaging (MRI) is vital for early diagnosis and treatment planning. Artificial intelligence (AI), especially deep learning,...

  • Review
  • Open Access
582 Views
85 Pages

In Vivo Models of Cardiovascular Disease: Drosophila melanogaster as a Genetic Model of Congenital Heart Disease

  • Theodora M Stougiannou,
  • Maria Koutini,
  • Fotios Mitropoulos and
  • Dimos Karangelis

Drosophila melanogaster (D. melanogaster) has been widely used in biology, including classical genetics, for almost a century. With the entire D. melanogaster genome sequenced and the existence of transgenic and mutant individuals, the species offers...

  • Article
  • Open Access
348 Views
15 Pages

A Retrospective Study Regarding the Implementation of Laparoscopy in Colon Cancer Through the Evaluation of Lymph Node Yield and Oncological Safety Margins in a Medium-Volume Center in Eastern Europe

  • Iulian Slavu,
  • Raluca Tulin,
  • Alexandru Dogaru,
  • Ileana Dima,
  • Cristina Orlov Slavu,
  • Marius Popescu,
  • Bogdan Nitescu,
  • Daniela-Elena Gheoca Mutu and
  • Adrian Tulin

Background: Laparoscopic surgical procedures are increasingly adopted for colorectal cancer because of their advantages in perioperative outcomes. However, their implementation in medium-volume centers (<50 laparoscopic resections per year) remain...

  • Article
  • Open Access
412 Views
13 Pages

CytoSorb® Hemadsorption During Microaxial Flow Pump (mAFP) Support in Cardiogenic Shock: A Propensity Score-Matched Cohort Study

  • Julian Kreutz,
  • Klevis Mihali,
  • Lukas Harbaum,
  • Georgios Chatzis,
  • Nikolaos Patsalis,
  • Styliani Syntila,
  • Bernhard Schieffer and
  • Birgit Markus

Background: Despite advances in temporary mechanical circulatory support (tMCS), patients with cardiogenic shock (CS) who are treated with a microaxial flow pump (mAFP; Impella®, Abiomed) still have a high mortality rate. A dysregulated systemic...

  • Systematic Review
  • Open Access
323 Views
20 Pages

Does Phototherapy Affect Ductus Arteriosus Closure in Preterm Infants ≤32 Weeks of Gestation, and Can We Influence This Through Chest Shielding? Review of the Literature and a Meta-Analysis

  • Marta Simon,
  • Zsuzsanna Gall,
  • Monika Rusneac,
  • Amalia Fagarasan,
  • Raluca Marian,
  • Madalina Anciuc-Crauciuc,
  • Andreea Racean,
  • Andrea Noemi Toth and
  • Manuela Cucerea

Background: Persistency of patent ductus arteriosus is the main cardiac condition in the preterm population born before 32 completed weeks of gestation with possible short- and long-term hemodynamic disturbances leading to vast morbidity. Jaundice is...

  • Article
  • Open Access
436 Views
24 Pages

Clinical and Therapeutic Insights into Sepsis: A Retrospective Observational Study of Inflammatory Markers, and Outcomes

  • Dragoș Ștefan Lazăr,
  • Adina-Alexandra Nanu,
  • Ilie-Andrei Condurache,
  • Casandra Bulescu,
  • Catrinel Tudosie,
  • Alexandra Ioana Grigore,
  • Corneliu Petru Popescu and
  • Simin Aysel Florescu

Introduction: Sepsis is a life-threatening condition caused by dysregulated host responses to infection, leading to organ failure and high mortality. Early recognition, especially in vulnerable populations, remains challenging due to variable present...

  • Article
  • Open Access
356 Views
16 Pages

Background/Objectives: Peripheral neuropathy (PN) triggers early oxidative stress, disrupting Schwann cell homeostasis. In this context, mitochondria serve as a primary source and vulnerable target of reactive oxygen species (ROS). Here, we investiga...

of 26

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Biomedicines - ISSN 2227-9059