Experimental Models to Study Tumor–Microenvironment Interactions
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 2813
Special Issue Editor
Interests: tumor secretome; pre-metastatic niche; tumor–microenvironment interactions; cancer models; cell adhesion; invasion and metastasis; breast cancer brain metastases
Special Issue Information
Dear Colleagues,
This Special Issue will focus on the currently available experimental models (in vitro, ex-vivo, and in vivo) used to study the paracrine communication between cancer cells and all different components of the tumor microenvironment.
The interaction between tumor cells and the different components of their microenvironment is bidirectional. Recent advances have shown that an understanding of the complex interactions of tumor cells with their adjacent microenvironment (composed of soluble and cellular components) are crucial to understand the mechanisms involved in tumor progression, such as epithelial–mesenchymal transition (EMT), migration, invasion (i.e., migration through connective tissue), metastasis formation, neovascularization, apoptosis, and chemotherapeutic drug resistance.
In order to understand the complex interaction between cancer cells and their microenvironment, it is fundamental to have the appropriate tools to study this process. Thus, in this Special Issue we aim to gather publications that focus on experimental models to study tumor–microenvironment interactions. Authors are invited to submit their original research, communications, and review articles under this topic.
Dr. Ana Sofia Ribeiro
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- in vitro models
- ex-vivo models
- in vivo models
- cancer models
- microenvironment
- metastatic niche
- immunomodulation
