Drug Resistance and Tumor Microenvironment in Human Cancers

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 33

Special Issue Editors


E-Mail Website
Guest Editor
CICS-UBI—Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal
Interests: cancer biology; tumor microenvironment; oncogenic signaling pathways; metabolism; hypoxia; acidosis; drug resistance

E-Mail Website
Guest Editor
CICS-UBI—Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal
Interests: cancer biology; cancer metabolism; tumor microenvironment; steroid hormones and receptors; drug resistance
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
CICS-UBI—Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal
Interests: cancer biology; estrogens; G protein-coupled estrogen receptor (GPER); tumor microenvironment; drug resistance

Special Issue Information

Dear Colleagues,

We are calling for manuscripts to be published in the Special Issue ‘Drug Resistance and Tumor Microenvironment in Human Cancers’ of the Biomedicines journal.

The tumor microenvironment is a critical contributor to triggering the acquisition of drug resistance. The development of resistance to therapy is a significant barrier to treatment and one of the major challenges in cancer translational research. Understanding the influence of the tumor microenvironment on cancer cell signaling and behavior towards drug resistance is crucial to identify new therapeutic strategies that might increase patients’ survival and life quality. This Special Issue aims to collect and publish recent discoveries on the influence of the tumor microenvironment in cancer drug resistance. Manuscripts describing research on the cellular and molecular basis of resistance to cancer therapy are welcome. Topics may include, but are not limited to, the role of cancer-associated fibroblasts, immune cells, epithelial cells, endothelial cells, acidosis, hypoxia, extracellular matrix proteins and other components of the tumor microenvironment in acquiring drug resistance. Articles identifying novel markers, new therapeutic targets and promising molecular and cellular drug resistance mechanisms will be highly preferred. Original contributions and review articles on this topic are welcomed.

We look forward to receiving your valuable contributions. 

Dr. Tiago Miguel Amaral Carvalho
Prof. Dr. Silvia Socorro
Dr. Marília Isabel Neto Figueira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer therapy
  • drug resistance
  • tumor microenvironment
  • targeted therapy
  • precision medicine
  • cancer-related mechanisms

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Published Papers

This special issue is now open for submission.
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