Tendinopathy and Myopathy: From Molecular Basis to Therapy

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 519

Special Issue Editors


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Guest Editor
1. Department of Physical Medicine and Rehabilitation, Linkou Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 333423, Taiwan
2. Department of Physical Medicine and Rehabilitation, Lotung Poh-Ai Hospital, Yilan 265501, Taiwan.
Interests: tendinopathy; myopathy

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Guest Editor
Chang Gung Memorial Hospital, Linkou, Taoyuan City, Guishan Township, Taiwan
Interests: aging proteomics; disease proteomics

Special Issue Information

Dear Colleagues,

Tendinopathy and myopathy are prevalent musculoskeletal disorders affecting a significant number of individuals. New developments in comprehending tendinopathy and myopathy emphasize an increasing acknowledgment of various biomarkers, microRNAs, lncRNAs, and cellular reactions implicated in their development. Advanced technologies now allow for quantitative assessments of tissue vascularity, echogenicity, and elasticity, providing detailed and precise data that enhance our understanding of various disease processes. Furthermore, upcoming therapeutic approaches encompass stem cells, exosomes, biomaterials, and nanomaterials. This Special Issue titled “Tendinopathy and Myopathy: From Molecular Basis to Therapy” highlights the progress in the pathogenesis, diagnosis, and treatment of tendinopathies and myopathies. We invite experts worldwide to submit their latest research on this topic. Original articles and reviews are all equally welcomed contributions.

Dr. Simon Fuk-Tan Tang
Dr. Carl Pai Chu Chen
Guest Editors

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Keywords

  • musculoskeletal disorder
  • tendinopathy
  • myopathy

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Published Papers (1 paper)

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Research

15 pages, 2590 KiB  
Article
Evaluating the Effectiveness of Ultrasound-Guided Subacromial-Subdeltoid Bursa and Coracohumeral Ligament Corticosteroid Injections With and Without Physiotherapy in Adhesive Capsulitis Treatment
by Chu-Wen Tang, Ting-Yu Lin, Peng-Chieh Shen and Fuk-Tan Tang
Biomedicines 2024, 12(12), 2668; https://doi.org/10.3390/biomedicines12122668 - 22 Nov 2024
Viewed by 250
Abstract
Background: The objective of this study was to investigate the effect of ultrasound-guided corticosteroid injection to the subacromial-subdeltoid bursa (SSB) and coracohumeral ligament (CHL) in treating adhesive capsulitis, with a particular focus on evaluating the potential benefits of regular electrotherapy and conventional [...] Read more.
Background: The objective of this study was to investigate the effect of ultrasound-guided corticosteroid injection to the subacromial-subdeltoid bursa (SSB) and coracohumeral ligament (CHL) in treating adhesive capsulitis, with a particular focus on evaluating the potential benefits of regular electrotherapy and conventional rehabilitation exercises. Methods: A total of 29 patients with unilateral shoulder pain and restricted shoulder range of motion (ROM) were included. Corticosteroids were delivered to the subacromial-subdeltoid bursa (SSB) and coracohumeral ligament (CHL) through a single percutaneous injection. Group 1 consisted of 18 patients who received injections only, while Group 2 comprised 11 patients who received injections in combination with regular physiotherapy. Shoulder Pain and Disability Index (SPADI) scores and ROM were assessed before the injection, and again at 4, 8, and 12 weeks following the intervention. A multivariate mixed-effects model with repeated measurements was conducted for the variables. Results: Electrotherapy and traditional rehabilitation exercises did not enhance the effectiveness of this injection approach. Pain, upper extremity function, and ROM in all planes were all significantly improved with a corticosteroid injection to the CHL and SSB. Conclusions: Physiotherapy did not offer additional benefits when combined with ultrasound-guided corticosteroid injection to the CHL and SSB. The injection alone significantly improved pain, disability, and ROM in patients with adhesive capsulitis. Further research is required to optimize current physiotherapy with electrotherapy and traditional rehabilitation exercises after ultrasound-guided corticosteroid injections. Full article
(This article belongs to the Special Issue Tendinopathy and Myopathy: From Molecular Basis to Therapy)
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