Feature Reviews in Molecular and Cellular Mechanisms of Inflammation and Tissue Regeneration

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2130

Special Issue Editor


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Guest Editor
Imagery Unit, Department of Platforms and Technology Research, French Armed Forces Biomedical Research Institute, 91223 Brétigny-sur-Orge, France
Interests: in situ macrophage characterization; in situ hybridization; cytokine expression
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Special Issue Information

Dear Colleagues,

Understanding the processes of inflammation and tissue regeneration after injury is of major scientific and clinical importance. Immune cells are a heterogeneous population of cells that acquire their functional specialization in response to micro-environmental alterations. For a long time, immune cells have been known to trigger inflammation and coordinate an efficient repair of damaged tissue. However, the molecular and cellular mechanisms by which they exert their effects are as yet mostly unknown. When repair is not coordinated, regeneration fails and fibrosis can take place. The investigation of immune cell sub-populations by different biological, molecular and cellular methods is essential in establishing new diagnostics for multiple diseases as well as therapeutic strategies for tissue repair. This Special Issue welcomes reviews articles focused on the molecular and cellular mechanisms of inflammation and tissue regeneration. Reviews have to most up-to-date and focus on the development of recent 10 years.

Dr. Krisztina Nikovics
Guest Editor

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Keywords

  • inflammation
  • tissue regeneration
  • immune cells
  • cytokine

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Published Papers (1 paper)

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Review

11 pages, 523 KiB  
Review
The Use of Hydrogel Dressings in Sulfur Mustard-Induced Skin and Ocular Wound Management
by Fanny Caffin, David Boccara and Christophe Piérard
Biomedicines 2023, 11(6), 1626; https://doi.org/10.3390/biomedicines11061626 - 2 Jun 2023
Cited by 3 | Viewed by 1743
Abstract
Over one century after its first military use on the battlefield, sulfur mustard (SM) remains a threatening agent. Due to the absence of an antidote and specific treatment, the management of SM-induced lesions, particularly on the skin and eyes, still represents a challenge. [...] Read more.
Over one century after its first military use on the battlefield, sulfur mustard (SM) remains a threatening agent. Due to the absence of an antidote and specific treatment, the management of SM-induced lesions, particularly on the skin and eyes, still represents a challenge. Current therapeutic management is mainly limited to symptomatic and supportive care, pain relief, and prevention of infectious complications. New strategies are needed to accelerate healing and optimize the repair of the function and appearance of damaged tissues. Hydrogels have been shown to be suitable for healing severe burn wounds. Because the same gravity of lesions is observed in SM victims, hydrogels could be relevant dressings to improve wound healing of SM-induced skin and ocular injuries. In this article, we review how hydrogel dressings may be beneficial for improving the wound healing of SM-induced injuries, with special emphasis placed on their suitability as drug delivery devices on SM-induced skin and ocular lesions. Full article
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