New Advances in the Treatment of Brain Tumors
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 30
Special Issue Editor
Special Issue Information
Dear Colleagues,
Remarkable advances over the past decade have reshaped how we treat brain tumors, including diffuse gliomas, glioblastoma, meningioma, pediatric embryonal tumors, and brain metastases. Progress in molecular taxonomy, modulation of the blood–brain barrier (BBB), image-guided surgery and radiotherapy, immuno-oncology, and AI-enabled clinical decision support is opening new therapeutic windows, yet durable benefits remain elusive for many patients. To help bridge discovery and practice, we introduce this Special Issue, “Advances in the Treatment of Brain Tumors.”
This Special Issue aims to showcase state-of-the-art strategies and translational breakthroughs that improve outcomes and quality of life for patients with primary and metastatic brain tumors. We welcome submissions that span the continuum from mechanistic insight to clinical validation, emphasize rigorous methodology and reproducibility, and articulate clear paths to bedside impact.
The scope includes, but is not limited to, the following topics: (i) advances in radiotherapy and radiosensitization; (ii) systemic therapies such as chemotherapy, targeted and epigenetic agents, antibody–drug conjugates, and radiopharmaceuticals; (iii) immuno-oncology (checkpoint blockade, vaccines, CAR-T/NK, myeloid modulation, and oncolytic virotherapy); (iv) BBB-crossing and locoregional delivery (focused ultrasound, convection-enhanced delivery, nanoparticles, and intrathecal/intraventricular routes); (v) biomarker-guided precision medicine using multi-omics, single-cell/spatial profiling, radiogenomics, and liquid biopsy; (vi) clinical trials and real-world evidence, including adaptive designs, patient-reported outcomes, neurocognition, survivorship, and health equity; and (vii) digital and AI tools for prognosis, treatment selection, and workflow integration. We encourage the submission of all article formats that advance this field.
Dr. Harim Koo
Guest Editor
Manuscript Submission Information
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Keywords
- neuro-oncology
- brain tumor
- cancer therapy
- precision medicine
- biomarkers
- drug delivery
- multi-omics
- neurosurgery
- clinical trials
- bioinformatics
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