Extracellular microRNAs in Inflammatory Diseases

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 2775

Special Issue Editor


E-Mail Website
Guest Editor
College of Korean Medicine, Dongguk University, Goyang 10326, Republic of Korea
Interests: inflammatory brain diseases; miRNA; ncRNA; ceRNA; biomarker; acupuncture; neuroscience; neurobiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

MicroRNAs (miRNAs), short non-coding RNA, are involved in various physiologic and pathologic processes, such as differentiation, development, inflammation, immune response, and cancer. Recently, emerging evidence show that miRNA in extracellular vesicle (EV) participates in transcriptional regulation through various pathways to promote or reduce the inflammatory response. However, the possible mechanisms that EV-miRNAs affect inflammation is still to be elucidated. In this special issue, we will focus on the role of extracellular miRNAs in controlling pivotal biological mechanisms that lead to pro-/anti-inflammatory effect, inflammatory cytokines regulation, inflammasome activation, immune cell responses, as well as various inflammation-related diseases. We invite authors in this exciting field to submit original research and review manuscripts to discuss the mechanisms of extracellular microRNAs on inflammation.

Dr. Seung-Nam Kim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • extracellular vesicles
  • exosome
  • MicroRNAs
  • inflammation
  • inflammasome
  • immune cell response
  • pro-/anti-inflammatory effect
  • inflammatory cytkine regulation
  • inflammatory diseases

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

16 pages, 693 KiB  
Review
The Extracellular MicroRNAs on Inflammation: A Literature Review of Rodent Studies
by Seri Lee, Jade Heejae Ko and Seung-Nam Kim
Biomedicines 2022, 10(7), 1601; https://doi.org/10.3390/biomedicines10071601 - 5 Jul 2022
Cited by 1 | Viewed by 2465
Abstract
Inflammation is an indispensable biological process stimulated by infection and injuries. Inflammatory mechanisms related to extracellular vesicles (EVs), which are small membrane structures carrying various molecules, were summarized in this review. Emerging evidence from animal studies has highlighted the role of EVs in [...] Read more.
Inflammation is an indispensable biological process stimulated by infection and injuries. Inflammatory mechanisms related to extracellular vesicles (EVs), which are small membrane structures carrying various molecules, were summarized in this review. Emerging evidence from animal studies has highlighted the role of EVs in modulating inflammatory responses, by transporting various molecules involved in host defense. In this review, we have discussed the role of EV miRNAs in inflammation. Rodent studies associated with extracellular miRNAs in inflammatory diseases, published from 2012 to 2022, were explored from PUBMED, EMBASE, and MEDLINE. A total of 95 studies were reviewed. In summary, EV-associated miRNAs play a key role in various diseases, including organ injury, immune dysfunction, neurological disease, metabolic syndrome, vesicular disease, arthritis, cancer, and other inflammatory diseases. Diverse EV-associated miRNAs regulate inflammasome activation and pro- and anti-inflammatory cytokine levels by targeting genes. Full article
(This article belongs to the Special Issue Extracellular microRNAs in Inflammatory Diseases)
Show Figures

Graphical abstract

Back to TopTop