Advanced Biomechanics in Bone Tissue Engineering

A special issue of Biomimetics (ISSN 2313-7673).

Deadline for manuscript submissions: closed (25 June 2024) | Viewed by 824

Special Issue Editor


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Guest Editor
Department of Architecture and Industrial Design, University of Campania, 81031 Aversa, Italy
Interests: materials science characterization; materials science engineering; biomaterials; biomechanics; advanced manufacturing
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Special Issue Information

Dear Colleagues,

Bone tissue engineering is a complex and dynamic bone remodeling process which requires the recruitment of osteoprogenitor cells, their proliferation, differentiation, and matrix formation. Innovative bone scaffolds and implants should provide mechanical support during the repair and regeneration of damaged or diseased bones, ensuring suitable biomechanical and biochemical environments to support normal cellular activity and molecular signaling systems.

A bioinspired and biomimetic approach will explore the potentiality of evolution-engineered natural materials showing not regular and orthotropic trabecular micro-structures such as those of the cancellous bone, marine sponge, leaves, or wood. Animal and vegetal reigns trabecular materials exploit anisotropy and morphology, increasing their functional efficiency, not only placing material where most is needed to resist applied loads but also introducing the ability to promote and facilitate bone regeneration.

Modern medicine is taking advantage of continuous progress in biomedical engineering. This Special Issue is dedicated to presenting the most promising recent research advancements of new biomimetic hybrid materials, scaffolds and implants, and innovative biomechanical research approaches, as well as reviewing results from a broad category related to applications using biomimetic architected structures in metals, ceramics, polymers, and their combinations in nanocomposites and hybrid materials.

The bone tissue biomechanics topics to exploit include, but are not limited to, the use of targeted biomolecules, mechanical properties, multi-scale porous scaffolds involving both micro and macro porosities, new structural controlled rate bioresorbable scaffolds, and engineering aspects such as design and 3D-additive fabrication techniques outlining the convergence between clinical applications and biomedical engineering from the perspective of innovative materials science and technologies.

Dr. Raffaella Aversa
Guest Editor

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Keywords

  • bone tissue engineering
  • biomechanically active scaffolds
  • metal additive scaffold manufacturing
  • structural bioresorbable materials
  • architected metamaterials
  • multiscale porous scaffolds
  • bioactive coatings and membranes
  • metallic smart biomaterials
  • ceramic smart biomaterials
  • polymeric smart biomaterials
  • biomechanics
  • biomimetics
  • nanocomposites
  • hybrid materials
  • bioresorbable ceramics
  • bioresorbable polymers
  • bioresorbable metals
  • polymer composites and nanomaterials
  • ceramic–polymeric hybrid systems
  • hybrid smart structures
  • functional biocoatings
  • new theoretical approaches for biomimetic material and prostheses
  • bionic prostheses based on smart materials
  • shape memory alloys

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Published Papers (1 paper)

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Research

17 pages, 16294 KiB  
Article
Adaptive Adjustments in Lower Limb Muscle Coordination during Single-Leg Landing Tasks in Latin Dancers
by Xiangli Gao, Tianle Jie, Datao Xu, János Gál, Gusztáv Fekete, Minjun Liang and Yaodong Gu
Biomimetics 2024, 9(8), 489; https://doi.org/10.3390/biomimetics9080489 - 13 Aug 2024
Viewed by 417
Abstract
Previous research has primarily focused on evaluating the activity of individual muscles in dancers, often neglecting their synergistic interactions. Investigating the differences in lower limb muscle synergy during landing between dancers and healthy controls will contribute to a comprehensive understanding of their neuromuscular [...] Read more.
Previous research has primarily focused on evaluating the activity of individual muscles in dancers, often neglecting their synergistic interactions. Investigating the differences in lower limb muscle synergy during landing between dancers and healthy controls will contribute to a comprehensive understanding of their neuromuscular control patterns. This study enrolled 22 Latin dancers and 22 healthy participants, who performed a task involving landing from a 30 cm high platform. The data were collected using Vicon systems, force plates, and electromyography (EMG). The processed EMG data were subjected to non-negative matrix factorization (NNMF) for decomposition, followed by classification using K-means clustering algorithm and Pearson correlation coefficients. Three synergies were extracted for both Latin dancers and healthy participants. Synergy 1 showed increased contributions from the tibialis anterior (p < 0.001) and medial gastrocnemius (p = 0.024) in Latin dancers compared to healthy participants. Synergy 3 highlighted significantly greater contributions from the vastus lateralis in healthy participants compared to Latin dancers (p = 0.039). This study demonstrates that Latin dancers exhibit muscle synergies similar to those observed in healthy controls, revealing specific adjustments in the tibialis anterior and medial gastrocnemius muscles among dancers. This research illustrates how dancers optimize control strategies during landing tasks, offering a novel perspective for comprehensively understanding dancers’ neuromuscular control patterns. Full article
(This article belongs to the Special Issue Advanced Biomechanics in Bone Tissue Engineering)
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