Biomimetic Materials for Anisotropic Tissue Regeneration

Dear Colleagues,

Anisotropic tissue engineering (e.g., tendon/ligament, nerve) offers a promising strategy to promote functional tissue recovery and then guide tissue repair and regeneration. Recently, biomaterials play an increasingly critical role in the success of tissue-engineering scaffolds. Particularly, numerous research groups have been trying to design and develop biomimetic biomaterials and advanced techniques based on recent momentous discoveries centered around the microenvironment of the extracellular matrix (ECM) and their interplay with cells in order to construct artificial organs and functional tissues for basic biological studies and clinical applications. Biomimetic ECM scaffolds with unique (bio) physicochemical cues, such as 2D topography/3D geometry, viscoelasticity, stiffness, wettability, material component and ECM proteins, etc., can significantly affect cell survival and mediate cell attachment, recruitment, viability, and the self-maintenance or differentiation of stem cells and anisotropic tissue/organ functions. This Special Issue aims to focus on the design and preparation of biomimetic ECM scaffolds relevant to anisotropic tissue repair and regeneration.

Dr. Huihua Yuan
Guest Editor

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