Oxidative Stress and Inflammation in Aging and Cancer: Biological Bases, Therapeutic Strategies and Opportunities
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 15 March 2025 | Viewed by 88
Special Issue Editor
Special Issue Information
Dear Colleagues,
Oxidative stress and inflammation are two interconnected processes, playing a crucial role in physiological and pathological conditions, such as aging and cancer. Oxidative stress is generated by an imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses, leading to damaged cells, proteins and DNA. This damage accelerates the aging process and increases the risk of developing cancer. In turn, chronic inflammation appears when the activation of the immune system is maintained over time. This state promotes the growth and spread of cancer cells, as well as contributes to age-related impairments. Moreover, oxidative stress can trigger inflammation, and chronic inflammation can lead to the establishment of the redox imbalance. Both processes can further exacerbate the aging-related manifestations and cancer development. Based on that, growing interest in developing therapeutic strategies targeting oxidative stress and inflammation against aging consequences and cancer are being reported. Antioxidant and anti-inflammatory drugs, as well as natural interventions, such as lifestyle modifications (diet and exercise) have shown promising results in reducing oxidative stress and inflammation, thereby exhibiting the potential of slowing down the aging process and reducing the risk of cancer.
Dr. Antonio Garrido
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ROS
- inflammatory compounds
- oxidative stress
- chronic inflammation
- aging
- cancer
- immunomodulation
- antioxidant strategies
- exercise
- nutrition
