Digestive Enzymes in Health and Disease
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Enzymology".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 195
Special Issue Editors
2. Department of Medical Biology, IMW, Jaczewskiego, Poland
Interests: peptide absorption and metabolism; animal models for orphan diseases
2. Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland
Interests: amylase metabolic regulatory features; animal models for human diseases
2. Departament of Interventional Dentistry, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland
Interests: animal models in dentistry; dietary factors and dental health
2. School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Parktown, Johannesburg 2193, South Africa
Interests: metabolic effects of dietary interventions and their implications for health and disease; metabolic responses to dietary stressors; glucose metabolism; hepatic steatosis induced by high-fructose and high-cholesterol diets; metabolic health markers; bioactive compounds in the attenuation of diet-induced metabolic abnormalities; therapeutic strategies for metabolic dysfunctions
Special Issue Information
Dear Colleagues,
We are pleased to announce the upcoming Special Issue of Biomolecules, titled ‘Digestive Enzymes in Health and Disease’. Biomolecules is focused on the structures and functions of bioactive molecules, the molecular mechanisms in which these biomolecules are involved, and the various applications of these biomolecules. The ‘Digestive Enzymes in Health and Disease’ Special Issue will explore the diverse roles of digestive enzymes in physiological processes, their implications in disease mechanisms, and their therapeutic potential in clinical applications, all of which are well within the journal’s scope.
Digestive enzymes are essential to maintaining metabolic homeostasis, aiding in nutrient digestion and absorption, and protecting against gastrointestinal dysfunction. Disruptions in digestive enzyme activity are associated with the development of disorders such as malabsorption syndromes and inflammatory bowel disease and metabolic conditions like obesity and diabetes. Recent advances in the research field offer novel insights into the functions of these digestive enzymes, many of which include ‘extra-digestive’ roles, paving the way for possible innovative therapeutic strategies. Thus, this Special Issue aims to deepen our understanding of digestive enzymes and their clinical relevance.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following themes:
- Biochemical and molecular mechanisms of digestive enzymes.
- Regulation of digestive enzyme activity in health and disease.
- Digestive enzymes and the gut microbiome.
- Role of enzymes in gastrointestinal and metabolic disorders.
- Therapeutic applications of digestive enzymes.
- Advances in enzyme replacement therapies.
This Special Issue will provide an opportunity for researchers to share their recent results and contribute to advancing the field.
We look forward to your contributions to this special issue.
Prof. Dr. Stefan G. Pierzynowski
Dr. Kateryna Pierzynowska
Dr. Piotr Wychowański
Dr. Janine Donaldson
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- digestive enzymes
- gastrointestinal health
- enzyme replacement therapy
- gut microbiome
- metabolic disorders
- enzyme regulation
- disease biomarkers
- inflammatory diseases
- nutrient absorption
- therapeutic enzymes
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