Harnessing the Immune System Against Solid Cancer: New Targets and Novel Therapeutic Approaches
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 31 March 2025 | Viewed by 31
Special Issue Editor
Interests: immune response in cancer; molecular mechanisms of immunosuppression ; cysteine proteases and their inhibitors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Immunotherapy has revolutionized the treatment of hematological malignancies, delivering sustained immune responses and prolonged patient survival. In the treatment of solid cancers, aside from melanoma, immunotherapy has faced less success due to the complex tumour microenvironment (TME), a major contributor to immune evasion. Harnessing the TME immune cells to combat these malignancies has shown promise, leading to the development of various immunotherapy approaches. Analysis of the intersection of specific cells within TME enables the detection of new clinical biomarkers for response to immune therapy. By comprehending and targeting the intricate interactions within the TME, these therapies can be refined to improve their effectiveness and broaden their application to a wider variety of solid tumours.
The scope of this Special Issue is to highlight the latest basic and clinical advancements in understanding interactions within TME. We aim to provide a platform for advancing research on identifying key targets and pathways associated with immune dysregulation within the TME, which that can be exploited for identifying new therapeutic targets and/or developing novel therapeutic strategies. This is of vital importance for surpassing current limitations and achieving enduring remission in treatment of solid cancer.
We warmly invite the submission of research and review articles that explore basic and methodological advancements in understanding the regulation of immune cell function within TME. Additionally, we encourage manuscripts that develop new tools to enhance immune cell function.
Dr. Milica Perišić Nanut
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immune response in cancer
- molecular mechanisms of immunosuppression
- cysteine proteases and their inhibitors
