Cellular Quiescence and Dormancy

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Genetics".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 40

Special Issue Editor


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Guest Editor
Department of Genetics, Evolution & Environment and Institute of Healthy Ageing, University College London, London, UK
Interests: gene regulation; genomics; transcriptomics; non-coding RNAs; genome function and evolution; fission yeast; cellular quiescence and ageing
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Special Issue Information

Dear Colleagues,

We are pleased to invite your contributions to this Special Issue on cellular quiescence and dormancy. Most cells, including those in our bodies, spend most of their time in non-dividing, quiescent states, yet these quiescent cells are much less studied than proliferating cells. Quiescence is characterized by a reversible arrest of cell proliferation, reprogrammed gene expression and metabolism, and increased stress resilience and longevity. Remarkably, some specialized dormant cells, like microbial spores or plant seeds, can survive harsh conditions for centuries. Human cells alternating between cellular quiescence and proliferation are critical for ageing- and disease-associated processes, including stem-cell function, tissue homeostasis and renewal, immune responses, and drug resistance of tumours.

This Special Issue aims to highlight the understudied genetic, regulatory and molecular adaptations that characterize cellular quiescence and dormancy across diverse organisms. Both original research articles and reviews are welcome. Research areas will cover various cellular and molecular processes featured in non-dividing, quiescent cells of microbes, fungi, plants, and animals as fundamental strategies for their normal development, function, and maintenance or for their long-term survival in the face of adverse conditions. We look forward to receiving your contributions.

Prof. Dr. Jürg Bähler
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • quiescent cells
  • dormant cells
  • biostasis
  • diapause
  • spores
  • dauer larva

Published Papers

This special issue is now open for submission.
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