Elucidating the Roles of Chromatin in Genomic Processes

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 60

Special Issue Editors


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Guest Editor
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: 3D chromatin structure; Hi-C; nucleosome positioning; super-resolution optical microscopy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: biophysics; real-time assembly of macromolecules; structure and function mechanisms of large complexes; single-molecule imaging techniques

Special Issue Information

Dear Colleagues,

All proteins that function in genomic processes operate on chromatin – nucleosomes have to be moved to allow access to the DNA or to prevent it. They may have to be chemically modified or replaced with “unconventional” variants. They may need to physically cluster together into nanodomains or “clutches”, which may then need to interact to form larger clusters. Over even longer distances, distant pairs of loci may have to be brought together in close physical proximity, or broader regions that can span megabase pairs may have to collapse into contact domains and then interact with other contact domains within compartments.

All of these properties of the chromatin, from the small to the large, from the chemical to the physical, from the persistent to the dynamic, are brought about by a wide range of mechanisms, many of which we are just beginning to understand in molecular detail. With this Special Issue, we would like to provide a platform to showcase some of the recent work focused on elucidating the roles of biomolecular complexes involved in affecting the properties of chromatin that are necessary for genomic processes. We welcome and encourage submissions in all formats (review, short communication, or research article) within this fascinating scope.

Prof. Dr. Daniel M. Czajkowsky
Guest Editor

Dr. Meijun Liu
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nucleosome positioning and occupancy
  • histone modifications
  • histone variants
  • nucleosome chaperones
  • nucleosome remodelers
  • insulator proteins
  • CTCF and cohesin
  • cis-regulatory elements
  • 3D genome structure
  • chromatin dynamics

Published Papers

This special issue is now open for submission.
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