The Role of Extracellular Vesicles in Drug Delivery
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 37
Special Issue Editor
Interests: translational research in medical oncology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are membrane-bound particles released from cells to deliver active biological molecules. Due to their unique biological properties, EVs recently emerged as efficient and safe drug delivery systems. EVs present low toxicity, low immunogenicity, and high stability in circulation, providing advantages over the use of synthetic delivery systems. Furthermore, EV drug delivery capabilities can be enhanced via EV engineering, which includes chemical and genetic EV modifications.
Several lines of evidence showed the potential application of EVs as drug delivery agents in various clinical settings, including cancer treatment, gene therapy, and conventional drug resistance. Although EVs represent a promising and versatile platform for drug delivery, challenges such as efficient isolation, purification, and understanding of EV biology need to be addressed in future studies.
In this Special Issue, we encourage investigators to contribute with high-quality original research, short communications, and review articles focused on EVs as novel drug delivery systems.
Dr. Davide Brocco
Guest Editor
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Keywords
- extracellular vesicles
- drug delivery systems
- extracellular vesicle engineering
- cancer treatment
- gene therapy
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