Fibronectin, Integrins and Related Molecules in Health and Diseases
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 32
Special Issue Editor
Interests: integrin-growth factor crosstalk; regulation of integrin activation; identification of new integrin ligands
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Integrins are receptors for extracellular matrix proteins (e.g., fibronectin), cell-surface proteins (e.g., ICAM-1 and VCAM-1), and soluble proteins (e.g., FGF and IGF). Recently, many new ligands such as cytokines have been identified. Integrins play critical roles in normal biology and development (e.g., wound healing) and are involved in the pathogenesis of diseases (e.g., cancer progression and metastasis). The RGD motif in the fibronectin cell-binding domain was identified as an integrin binding site in the 1980s, and since then we have witnessed the rapid development of RGD-based integrin antagonists. This research area is rapidly changing thanks to new technologies and tools. We are setting up this Special Issue to publish new discoveries in the integrin field with the aim of bringing the basic science to bedside more efficiently.
Prof. Dr. Yoshikazu Takada
Guest Editor
Manuscript Submission Information
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Keywords
- integrin
- fibronectin
- cytokines
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