Therapeutic Applications of Neural Stem Cells & Extracellular Vesicles
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 474
Special Issue Editor
2. Department of Radiology, Long School of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229-3900, USA
Interests: Parkinson’s disease; stroke; traumatic brain injury (TBI); multiple sclerosis (MS); human neural stem cells (NSCs); non human primate studies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biologics involving neural stem cells (NSCs) and extracellular vesicles (EVs) are transforming therapeutic approaches for neurological disorders. Over the past five years, neural stem cell-derived progeny and extracellular vesicles have made their way to clinical trials as potential treatments for intractable diseases, such as Parkinson’s disease, Alzheimer disease, dementias, amyotrophic lateral sclerosis, stroke, traumatic brain injury and spinal cord injury. However, there still remain critical challenges in translating these therapies to patients.
In this Special Issue, we will address the current progress and challenges in the development of therapeutic NSCs and EVs: 1) methods for controlling the identity, purity and potency of these biologics, in order to produce optimal therapeutic effects; 2) their isolation, perpetuation and characterization; 3) their impact of cellular composition and delivery methods on efficacy and translation from animal models to patients.
Dr. Marcel M. Daadi
Guest Editor
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Keywords
- translational research
- biologics
- regenerative medicine
- neural stem cells
- extracellular vesicles
- animal models
- neurological disorders
- stem cell transplantation therapy
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