Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Illumination of Biophysical Mechanisms by Hydrogen Exchange: A Themed Issue in Honor of Professor S. Walter Englander
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 2124 | Submission Open
Keywords: hydrogen exchange chemistry; HX– NMR; HX-MS; protein folding; allostery; protein binding; protein thermodynamics; protein biophysics; protein function
The Role of P-type ATPases in Health and Diseases submission deadline 31 Aug 2024 | 2 articles | Viewed by 2121 | Submission Open
Keywords: P-type ATPases; Na; K-ATPase; H-ATPase; H; K-ATPase; Ca-ATPase; Cu-ATPase; phospholipid flippases; genetic disease
(This special issue belongs to the Section Cellular Biochemistry)
Key Molecules in Traditional Medicine: From Molecular Mechanisms to Therapies Strategies
edited by and
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1441 | Submission Open
Keywords: natural compounds; traditional medicine; biomolecules in medicinal herbs; molecular changes caused by traditional medicine treatments
(This special issue belongs to the Section Natural and Bio-derived Molecules)
The Central Role of Mitochondrial Protein VDAC1 in Human Diseases – Honorary Special Issue Commemorating the Work of Prof. Varda Shoshan-Barmatz
edited by Jay H. Chung
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1131 | Submission Open
Keywords: apoptosis; ferroptosis; inflammation; metabolism; mitochondria; oxidative stress; pyroptosis; VDAC; cancer
(This special issue belongs to the Section Cellular Biochemistry)
Two Billion Years of Sex submission deadline 31 Aug 2024 | Viewed by 308 | Submission Open
Keywords: sex chromosomes; sex determination; separate sexes; mating types; XY; ZW
(This special issue belongs to the Section Molecular Biology)
Cannabinoids in Neurobehavioral Modulation submission deadline 31 Aug 2024 | Viewed by 205 | Submission Open
Keywords: cannabinoids; neurobehavior; brain diseases; therapeutic; translational
(This special issue belongs to the Section Molecular Biology)
Molecular Biomarkers in Cardiology 2024
edited by
submission deadline 31 Aug 2024 | Viewed by 199 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pathology and histology; carotid plaques and histology; endothelium and endothelial dysfunction; veins diseases; arrhythmias; heart
(This special issue belongs to the Section Molecular Biomarkers)
Properties and Functions of Endometrial Stromal Cells submission deadline 31 Aug 2024 | Viewed by 179 | Submission Open
Keywords: endometrium; endometriosis; molecular reproduction; implantation; decidualization; placentation; inflammation; reproductive endocrinology; assisted reproductive technology; molecular reproductive biology
(This special issue belongs to the Section Molecular Reproduction)
Next-Generation Nutraceuticals: Unlocking New Pathways for Cellular Health beyond the Foods submission deadline 31 Aug 2024 | Viewed by 126 | Submission Open
Keywords: nutraceuticals; cellular health; cellular aging mechanisms; chronic diseases; immune balance
Lymphangiogenesis in Health and Disease
edited by Rui-Cheng Ji
submission deadline 10 Sep 2024 | Viewed by 326 | Submission Open
Keywords: lymphatic endothelial cells; lymphatic vessels; lymphangiogenic molecules
(This special issue belongs to the Section Molecular Medicine)
Host Molecules and Molecular Mechanisms in Insects and Crustaceans submission deadline 10 Sep 2024 | Viewed by 242 | Submission Open
Keywords: insects; crustaceans; disease control and management; evolutionary biology; environmental monitoring and conservation
Molecular Plant Reproduction: From Cells to Nature
edited by
submission deadline 15 Sep 2024 | 8 articles | Viewed by 17293 | Submission Open
Keywords: botany; cell-to-cell communication; embryo development; endosperm development; floral development; gametogenesis; genome editing; genomics; metabolomics; meiosis; plant– environment interactions; transcriptomics
(This special issue belongs to the Section Molecular Reproduction)
Molecular Mechanism Investigations into Membrane Fusion
edited by James McNew
submission deadline 15 Sep 2024 | 6 articles | Viewed by 10130 | Submission Open
(This special issue belongs to the Section Cellular Biochemistry)
Cancer Immunotherapy and the PD-1/PD-L1 Checkpoint Pathway submission deadline 15 Sep 2024 | 3 articles | Viewed by 5262 | Submission Open
Keywords: immunotherapy; biomarkers; PD-1/PD-L1
(This special issue belongs to the Section Molecular Biology)
From the Past to the Present: Unveiling the Role of Biomolecules in Clinical History submission deadline 15 Sep 2024 | 3 articles | Viewed by 3901 | Submission Open
Keywords: biomolecules; clinical application; history; anemia; neurodegeneration; cancer
(This special issue belongs to the Section Molecular Medicine)
Tuberculosis: Immunopathogenesis and Therapeutic Strategies submission deadline 15 Sep 2024 | 2 articles | Viewed by 2932 | Submission Open
Keywords: tuberculosis; drug resistance; granulomatous inflammation; pathogenesis; immune responses; immunomodulation; host-directed therapy; antimicrobial treatment; antimicrobial mechanisms; antimicrobial agents
(This special issue belongs to the Section Molecular Medicine)
Placental-Related Disorders of Pregnancy II submission deadline 15 Sep 2024 | 1 articles | Viewed by 2006 | Submission Open
Keywords: placenta; preeclampsia; intrauterine growth restriction; placental abruption; placenta accrete; biomolecules; fetal programming; maternal programming; endothelial dysfunction; inflammation; oxidative stress
(This special issue belongs to the Section Molecular Medicine)
Research on Fatty Acid Oxidation and Fatty Acid Oxidation Disorders submission deadline 15 Sep 2024 | Viewed by 308 | Submission Open
Keywords: fatty acid oxidation; fatty acid oxidation disorders; regulation of fatty acid oxidation; therapeutics
(This special issue belongs to the Section Cellular Biochemistry)
Bcl-2 Family Proteins in Human Health and Diseases submission deadline 15 Sep 2024 | Viewed by 178 | Submission Open
Keywords: Bcl-2; cancer; signaling; therapy; apoptosis; mitochondria
Roles of Alpha-1 Antitrypsin in Human Health and Disease Models
edited by
submission deadline 15 Sep 2024 | Viewed by 112 | Submission Open
Keywords: alpha-1 antitrypsin; serine proteinase inhibitor (SERPIN); autoimmunity; inflammation; aging; cancer
Gap Junctions and Connexins in Health and Disease, 2nd Edition submission deadline 20 Sep 2024 | 1 articles | Viewed by 2237 | Submission Open
Keywords: connexin; connexon; hemichannel; gap junction; electrical synapse; communication; bystander effect
(This special issue belongs to the Section Molecular Medicine)
Extracellular Vesicles as Biomarkers and Pathologic or Therapeutic Agents in Motor Neuron Diseases submission deadline 20 Sep 2024 | Viewed by 307 | Submission Open
(This special issue belongs to the Section Biological Factors)
The Role of Tau Protein in Neurodegenerative Diseases
edited by and Valeria Melis
submission deadline 20 Sep 2024 | Viewed by 265 | Submission Open
Keywords: tau biology; toxicity; utility as a biomarker and for diagnoses; cellular and molecular mechanisms of neuropathology; mechanisms of the aggregation and formation of filaments and tangles; all aspects of tau genetics; tau and the immune system; tau as a therapeutic target: current status and progress
(This special issue belongs to the Section Biomacromolecules: Proteins)
Novel Insights into the Role of Autoantibodies in Diseases—2nd Edition
edited by
submission deadline 20 Sep 2024 | Viewed by 81 | Submission Open
Keywords: B cells; autoantibodies; peripheral blood; biomarkers; autoimmune diseases
(This special issue belongs to the Section Molecular Biomarkers)
Artificial Intelligence (AI) in Biomedicine submission deadline 30 Sep 2024 | 9 articles | Viewed by 18231 | Submission Open
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants
edited by
submission deadline 30 Sep 2024 | 8 articles | Viewed by 15009 | Submission Open
Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems
(This special issue belongs to the Section Cellular Biochemistry)
Neurological Disorders: From Molecular Mechanisms to Therapy Strategies submission deadline 30 Sep 2024 | 4 articles | Viewed by 14800 | Submission Open
Keywords: neurodegeneration; neuroprotection; novel therapies; natural molecules
(This special issue belongs to the Section Molecular Biology)
Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives submission deadline 30 Sep 2024 | 7 articles | Viewed by 11827 | Submission Open
Keywords: diet; nutrients; obesity; inflammation; fat; glucose intolerance; insulin resistance; fatty liver disease; metabolic syndrome
(This special issue belongs to the Section Molecular Medicine)
Novel Molecules for Cancer Treatment (2nd Edition) submission deadline 30 Sep 2024 | 4 articles | Viewed by 11220 | Submission Open
Keywords: cancer; small molecules; antibody– drug-conjugated; tyrosine kinase inhibitors; target therapy; monoclonal antibodies; immunotherapy; natural compounds
(This special issue belongs to the Section Molecular Medicine)
Functional Peptides and Their Interactions submission deadline 30 Sep 2024 | 4 articles | Viewed by 7665 | Submission Open
Keywords: naturally occurring peptides; peptide engineering; peptide interactions; peptide self-assembly; peptide structure; small proteins; molecular therapeutics; biomaterials; biocatalysts
(This special issue belongs to the Section Molecular Structure and Dynamics)
Advances in β3-Adrenoceptor submission deadline 30 Sep 2024 | 4 articles | Viewed by 7256 | Submission Open
Keywords: β 3-adrenoceptor; cardiovascular diseases; cancer; prematurity; hypoxia/hyperoxia; neurodegenerative diseases; retinopathy
(This special issue belongs to the Section Molecular Biology)
Interface of Aging and Biomaterials II
edited by
submission deadline 30 Sep 2024 | 3 articles | Viewed by 5627 | Submission Open
Keywords: aging; senescence; geroscience; biomolecules; biomaterials; biocompatibility; nanoparticles; hydrogels
(This special issue belongs to the Section Biological and Bio- Materials)
Cellular and Molecular Mechanisms of Endometriosis
edited by , Alessandra Andrisani and Chiara Sabbadin
submission deadline 30 Sep 2024 | 4 articles | Viewed by 5351 | Submission Open
Keywords: endocrine dysfunction in endometriosis; glycosylphosphatidylinositols (GPIs) and GPI-anchored proteins; oxidative stress markers (glutathione; carbonic anhydrase; etc.); endometriosis and deep endometriosis; endometriosis-related immune system
(This special issue belongs to the Section Molecular Biology)
Novel Insights into Autoimmune/Autoinflammatory Skin Diseases submission deadline 30 Sep 2024 | 3 articles | Viewed by 4788 | Submission Open
Keywords: autoimmune/autoinflammatory skin diseases; omics; bioinformatics; pathogenesis; tailored medicine
(This special issue belongs to the Section Molecular Medicine)
Molecular Advances in Mechanism and Regulation of Lifespan and Aging
edited by Mark McCormick
submission deadline 30 Sep 2024 | 1 articles | Viewed by 3644 | Submission Open
Keywords: aging; lifespan; healthspan
(This special issue belongs to the Section Molecular Biology)
Programmed Cell Death (Apoptosis): Molecular Mechanisms and Implications for New Drug Discovery submission deadline 30 Sep 2024 | 1 articles | Viewed by 2163 | Submission Open
Keywords: programmed cell death; apoptosis; molecular aspects of apoptosis; apoptosis regulation; drug discovery; emerging therapeutic approaches
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Profiling and Identification of Molecular Signatures Associated with Natural Products
edited by
submission deadline 30 Sep 2024 | 2 articles | Viewed by 2100 | Submission Open
Keywords: natural product; molecular mechanisms; repurposed molecules; disease model; human health
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Biomarkers of Cardiovascular and Cerebrovascular Diseases submission deadline 30 Sep 2024 | 2 articles | Viewed by 1851 | Submission Open
Keywords: biomarkers; cardiovascular disease; cerebrovascular disease; cardiovascular therapy; diagnosis
(This special issue belongs to the Section Molecular Biomarkers)
Aptamer Therapeutics in Cancers: New Advances and Future Trends submission deadline 30 Sep 2024 | 1 articles | Viewed by 1804 | Submission Open
Keywords: aptamers; cancer; targeted therapy; aptamer-based conjugates; aptamer-conjugated nanoparticles
(This special issue belongs to the Section Molecular Medicine)
The Role of Cholinesterases in Alzheimer’s Disease and Other Neurodegenerative Disorders
edited by
submission deadline 30 Sep 2024 | 2 articles | Viewed by 1774 | Submission Open
Keywords: Alzheimer’ s disease; acetylcholinesterase; butyrylcholinesterase; enzymatic properties; non-enzymatic properties; neuroinflammation; drug development; neuroimaging
(This special issue belongs to the Section Natural and Bio-derived Molecules)
New Insights into Mechanisms and Therapeutics for Cardiovascular Disorders
edited by , and Tarun W. Dasari
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1526 | Submission Open
Keywords: brain heart-axis; heart & stroke; stress-induced cardiomyopathy; cardiovascular disease
(This special issue belongs to the Section Molecular Medicine)
Recent Trends in Kidney and Cardiovascular Diseases
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1349 | Submission Open
Keywords: chronic kidney disease; cardiovascular risk; albuminuria; epidemiology; estimated glomerular filtration rate
(This special issue belongs to the Section Molecular Medicine)
Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders submission deadline 30 Sep 2024 | 1 articles | Viewed by 955 | Submission Open
Keywords: insulin receptor substrates; microglia; degenerative diseases; psychiatric disorders; nutrition
(This special issue belongs to the Section Molecular Medicine)
Rare Diseases: From Molecular Pathways to Therapeutic Strategies 2.0
edited by
submission deadline 30 Sep 2024 | Viewed by 571 | Submission Open
Keywords: adeno-associated virus  ; gene editing  ; metabolic diseases  ; lysosomal disorders  ; CRISPR  ; inborn errors of metabolism  ; neuromuscular disease
(This special issue belongs to the Section Molecular Medicine)
Insights into the Oral Microbiome and Its Modulation submission deadline 30 Sep 2024 | Viewed by 385 | Submission Open
Keywords: oral microbiome; oral infectious diseases; systemic disease
(This special issue belongs to the Section Molecular Biology)
Glial Cross-Talk in Central Nervous System Health and Disease submission deadline 30 Sep 2024 | Viewed by 376 | Submission Open
Keywords: glial physiology; glial cross-talk in CNS homeostasis; glial cross-talk in neuroinflammation; glial cross-talk in CNS diseases
Epigenetics in Parathyroid Tumors submission deadline 30 Sep 2024 | Viewed by 274 | Submission Open
Keywords: parathyroid disorders; parathyroid adenomas; parathyroid cancers; epigenetics; LncRNAs; microRNAs; circular RNAs; DNA methylation; DNA acetylation
(This special issue belongs to the Section Molecular Medicine)
Novel Insights on Cancer Stem Cells
edited by
submission deadline 30 Sep 2024 | Viewed by 234 | Submission Open
Keywords: cancer stem cells; cancer initiating cells; stemness; self-renewal; therapy resistance; epigenetic reprogramming
(This special issue belongs to the Section Molecular Medicine)
Gene Mutations in Retinal Dystrophies
edited by Benedetto Falsini and
submission deadline 30 Sep 2024 | Viewed by 206 | Submission Open
Keywords: genes; retina; inherited retinal dystrophies; phenotype
Plant-Microbe-Insect Interactions
edited by and Xueke Gao
submission deadline 30 Sep 2024 | Viewed by 198 | Submission Open
Keywords: plant– microbe– insect interactions; plant defense; insects; pest control; microbiology
(This special issue belongs to the Section Cellular Biochemistry)
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