Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Developments in Biophysical Studies of Cell Membranes: Second Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 227 | Submission Open
Keywords: membrane biophysics; cell membranes; model cell membranes
(This special issue belongs to the Section Molecular Biophysics)
Necrotic Cell Death Mechanisms and Therapies
edited by and
submission deadline 31 Oct 2024 | Viewed by 222 | Submission Open
Keywords: necrosis; mitochondria; lysosomes; reactive oxygen species (ROS); calcium signalling; caspase-independent proteases: serine proteases like CELA; ELA; as well as cathepsin C and B etc.; heat shock proteins (HSPs); epigenetics; necrosis in diseases and therapeutic intervention
(This special issue belongs to the Section Cellular Biochemistry)
Retinal Diseases: Molecular Mechanisms and Therapies
edited by and Raquel Boia
submission deadline 31 Oct 2024 | Viewed by 184 | Submission Open
Keywords: retinal diseases; molecular mechanisms; therapeutic strategies; vision impairment; gene therapy; retinal degeneration; neuroprotection; innovative treatments
(This special issue belongs to the Section Cellular Biochemistry)
Advances in Drug Repurposing: New Functions for Existing Molecules
edited by
submission deadline 31 Oct 2024 | Viewed by 175 | Submission Open
Keywords: cancer; therapeutics; re-use; small molecule inhibitors; mechanisms of action
Molecular Targets for Breast Cancer Therapy, 2nd Edition submission deadline 31 Oct 2024 | Viewed by 162 | Submission Open
Keywords: breast cancer; molecular targets; signaling pathways; proliferation; survival; resistance; crosstalk
(This special issue belongs to the Section Molecular Medicine)
Molecular Biomarkers of Thyroid Cancer
edited by Laura Sterian Ward, Lucas Leite Cunha and
submission deadline 31 Oct 2024 | Viewed by 146 | Submission Open
Keywords: gene polymorphisms; Hashimoto disease; thyroid papillary carcinoma; thyroid neoplasms; biomarkers; microRNA; single nucleotide variants (SNP); oncology biomarker profiling; immunology; microenvironment
(This special issue belongs to the Section Molecular Biomarkers)
DNA Damage, Mutagenesis, and Repair Mechanisms
edited by , Sofie Lautrup and Péter Csaba Huszthy
submission deadline 31 Oct 2024 | Viewed by 139 | Submission Open
Keywords: DNA repair; BER; NER; HR; NHEJ; A-EJ; MMR; DDR; TCR; aging
Airway Diseases: Molecular Updates and Perspectives submission deadline 31 Oct 2024 | Viewed by 114 | Submission Open
Keywords: airway disease; molecular mechanisms; drugs; models
New Insights into Protein Aggregation in Condensed and Amyloid States
edited by
submission deadline 10 Nov 2024 | 1 articles | Viewed by 609 | Submission Open
Keywords: proteinopathies; protein aggregation; physico-chemical and biological properties of amyloid fibrils and protein condensates; signal and light transduction; interaction with lipid membranes; aggregating protein interactomes; bioinformatics and machine learning; molecular dynamics
(This special issue belongs to the Section Biomacromolecules: Proteins)
Protein Structure Prediction in Drug Discovery II submission deadline 15 Nov 2024 | 3 articles | Viewed by 7301 | Submission Open
Keywords: protein structure prediction; drug design; docking; virtual screening; drug discovery; machine learning; alphafold
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Molecular Insights into Treatment and Prognosis of Autoimmune Bullous Diseases
edited by Kristina Seiffert-Sinha and Animesh A. Sinha
submission deadline 15 Nov 2024 | Viewed by 101 | Submission Open
Keywords: autoimmunity; blistering; gene expression; immunome; keratinocyte; pathomechanism; proteome; skin
New Insight into Vector-Borne Diseases: 2nd Edition
edited by
submission deadline 15 Nov 2024 | Viewed by 84 | Submission Open
Keywords: host– pathogen interaction; vector biology; vector competence; arthropod-borne virus
Novel Biomarkers of Kidney Diseases: Second Edition submission deadline 15 Nov 2024 | Viewed by 84 | Submission Open
Keywords: biomarker; kidney disease; fibrosis; proteomics; metabolomics
Calcium Signaling in Cell Function and Dysfunction
edited by and Sofia Zanin
submission deadline 15 Nov 2024 | Viewed by 67 | Submission Open
Keywords: calcium signaling; calcium regulation; cell function; human pathology
Role of Matrix Metalloproteinase in Health and Disease
edited by Ali A. Hussain
submission deadline 15 Nov 2024 | Viewed by 64 | Submission Open
Keywords: matrix metalloproteinases (MMPs); regulatory aspects of MMPs; MMPs and tissue ageing; MMPs in diseases; MMPs as therapeutic targets
Nitrogen Signaling, Transport, and Function in Plants
edited by
submission deadline 20 Nov 2024 | 3 articles | Viewed by 10008 | Submission Open
Keywords: nitrogen assimilation; nitrogen sensing; nitrogen transport; nitrogen signaling; primary nitrate response; systemic nitrogen signaling
(This special issue belongs to the Section Biological Factors)
Heart Diseases: Molecular Mechanisms and New Therapies
edited by Glen Pyle
submission deadline 20 Nov 2024 | 1 articles | Viewed by 1003 | Submission Open
Keywords: heart failure; heart disease; myocardial; molecular mechanisms; therapies
(This special issue belongs to the Section Molecular Medicine)
Role of Iron Dysregulation in Chronic Inflammatory Diseases and Their Complications
edited by
submission deadline 20 Nov 2024 | Viewed by 309 | Submission Open
Keywords: iron; oxidative stress; ferroptosis; inflammation; chronic disease; metabolism; mitochondrial dysfunction
(This special issue belongs to the Section Molecular Medicine)
State-of-the-Art Cardio-Oncology
edited by
submission deadline 20 Nov 2024 | Viewed by 294 | Submission Open
(This special issue belongs to the Section Chemical Biology)
Experimental and Theoretical Approaches to Protein-Targeting Drug Discovery II submission deadline 29 Nov 2024 | 1 articles | Viewed by 1822 | Submission Open
Keywords: proteins; peptides; amyloid; aptamers; molecular docking; Alzheimer disease; Parkinson’ s disease; neurodrugs; biotechnological enzymes; antiviral drugs; vaccines; biomolecular targets; COVID-19; SARS-CoV-2; spike protein; peptide aggregation; drug repurposing; natural products; synthetic antivirals; anticancer therapeutics
(This special issue belongs to the Section Chemical Biology)
State-of-the-Art Biophysics, Biochemistry and Molecular Biology in China submission deadline 30 Nov 2024 | 17 articles | Viewed by 44700 | Submission Open
Keywords: Molecular modelling; molecular dynamics simulation; protein-protein interaction; protein folding; Bioinformatics; molecular docking; drug design; bio-nanomaterial interface; molecular machine; functional biomacromolecule design and optimization; functional regulation of RNA/DNA; microbiota; multimodal data; machine learning; vaccines
(This special issue belongs to the Section Molecular Biophysics)
Unraveling Mysteries of Heme Metabolism submission deadline 30 Nov 2024 | 7 articles | Viewed by 13930 | Submission Open
Keywords: heme synthesis; heme metabolism; metabolic disorders; tetrapyrroles; heme proteins
(This special issue belongs to the Section Molecular Biology)
Molecular and Cellular Basis for Rare Genetic Diseases submission deadline 30 Nov 2024 | 5 articles | Viewed by 11672 | Submission Open
Keywords: neurodevelopment; intellectual disability; neurodegeneration; rare genetic diseases; systems biology; membrane trafficking; epigenetics; metabolism
(This special issue belongs to the Section Cellular Biochemistry)
Biomolecular Approaches and Drugs for Neurodegeneration submission deadline 30 Nov 2024 | 5 articles | Viewed by 11329 | Submission Open
Keywords: proteins; peptides; amyloid; Alzheimer disease; Parkinson’ s disease; neurodrugs; G-quadruplex nucleic acids; biotechnology; biomolecular targets; peptide aggregation; natural products; synthetic drugs; antiamyloid therapeutics; machine learning
(This special issue belongs to the Section Chemical Biology)
Molecular Mechanisms of Alpha-Synuclein in Parkinson's Disease and Other Synucleinopathies submission deadline 30 Nov 2024 | 4 articles | Viewed by 8739 | Submission Open
Keywords: alpha-synuclein; molecular mechanisms; movement disorders; Parkinson’ s disease; dementia with lewy bodies; multiple-system atrophy; biomarkers; biochemistry; risk factors
(This special issue belongs to the Section Molecular Medicine)
Dysregulation of Calcium Signaling in Pathological Processes
edited by
submission deadline 30 Nov 2024 | 5 articles | Viewed by 8710 | Submission Open
Keywords: Ca2+-ATPases; calmodulinopathies; cancer; cardiovascular diseases; channelopathies; endocrine diseases; mitochondrial diseases; muscle diseases; neurodegenerative diseases; troponin C
(This special issue belongs to the Section Molecular Medicine)
Brain Sterols: Biosynthesis and Physiology in Health and Disease submission deadline 30 Nov 2024 | 4 articles | Viewed by 8470 | Submission Open
Keywords: sterol biosynthesis; sterol turnover; oxysterol; brain; cholesterol; development; aging; medication side effects; inborn errors of sterol biosynthesis; DHCR7
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Molecular Mechanisms of Infectious Pathogen Adaptation, Emergence, and Re-emergence submission deadline 30 Nov 2024 | 2 articles | Viewed by 3864 | Submission Open
Keywords: pathogen; structural biology; tuberculosis; function; molecular mechanism
(This special issue belongs to the Section Molecular Medicine)
Recent Developments in Mesenchymal Stem Cells submission deadline 30 Nov 2024 | 3 articles | Viewed by 3723 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; secretome
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Mechanisms of Life-Extending Biomolecules and Interventions with Medical and Technological Implications
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 3361 | Submission Open
Keywords: biomolecules; genes; molecular and metabolic mechanisms; model systems; humans
(This special issue belongs to the Section Molecular Biology)
New Insights into Reactive Oxygen Species in Cell Death and Immunity
edited by , and Dhia Azzouz
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2452 | Submission Open
Keywords: reactive oxygen species (ROS); cell death; immune response; ROS-mediated diseases; tools to study ROS
(This special issue belongs to the Section Cellular Biochemistry)
Role of Epigenetics in Organ Fibrosis
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2077 | Submission Open
Keywords: chronic heart disease; cardiac fibrosis; heart failure; fibroblast; cardiomyocyte; DNA methylation; histone modification; non-coding RNA; gene therapy
(This special issue belongs to the Section Molecular Genetics)
State of the Art and Perspectives in Antimicrobial Peptides
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1728 | Submission Open
Keywords: antimicrobial peptides; AMPs; chemical modification of AMPs; function; structure; synthesis
(This special issue belongs to the Section Molecular Medicine)
Human Reproductive Biology: Uncertainties and Controversies
edited by , and Paola Bianchi
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1626 | Submission Open
Keywords: molecular reproduction; endometriosis; endometrium; implantation; decidualization; placenta; cellular senescence; prostaglandin; inflammation; pregnancy; reproduction; implantation; decidualization; endometriosis; assisted reproductive technology; molecular reproductive biology; reproductive biology; reproductive immunology; reproductive medicine; reproductive endocrinology; molecular regulation of reproductive processes; embryo development; reproductive biology; gametogenesis and fertilization
(This special issue belongs to the Section Molecular Reproduction)
Intracerebral Hemorrhage: Advances in Preclinical Studies: 2nd Edition submission deadline 30 Nov 2024 | 1 articles | Viewed by 1034 | Submission Open
Keywords: neuroinflammation; oxidative stress; neurodegeneration; neurological deficits; blood– brain barrier damage
(This special issue belongs to the Section Molecular Medicine)
Biomarkers in Metabolic Diseases, 2nd Edition submission deadline 30 Nov 2024 | 1 articles | Viewed by 584 | Submission Open
Keywords: metabolic disorders; inborn errors of metabolism; surrogate biomarkers; biochemical markers; diagnostic markers; newborn screening; molecular analyses; metabolomics; disease progression; treatment efficacy
(This special issue belongs to the Section Molecular Biomarkers)
Recent Advances in the Enzymatic Synthesis of Bioactive Compounds submission deadline 30 Nov 2024 | Viewed by 320 | Submission Open
Keywords: biocatalysis; biotransformation; enzyme-catalyzed reactions; whole-cell catalysis; green chemistry; enzymes; phenolic compounds; polyphenols; lipases; lipophilization; enzymatic synthesis; esterification; transesterification; green and sustainable chemistry approaches; lipid modification
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Vitamin D in Health and Disease—Honorary Special Issue Commemorating the Work of Dr. Luminita A. Stanciu submission deadline 30 Nov 2024 | Viewed by 313 | Submission Open
Keywords: vitamin D; immune cells; innate immunity; respiratory diseases; allergy; infections; metabolic disorders; cellular metabolism
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms of Male Infertility submission deadline 30 Nov 2024 | Viewed by 269 | Submission Open
Keywords: male infertility; microRNA; NGS; molecular mechanism
(This special issue belongs to the Section Molecular Reproduction)
Melanin-Related Biomolecules: Synthesis, Properties and Applications
edited by Kazumasa Wakamatsu and
submission deadline 30 Nov 2024 | Viewed by 231 | Submission Open
Keywords: melanin; skin aging; hair color; photoaging; antioxidant action; UV protection; cosmetology; display technology; food industry
(This special issue belongs to the Section Molecular Biology)
Recent Advances in Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases: 2nd Edition
edited by
submission deadline 30 Nov 2024 | Viewed by 217 | Submission Open
Keywords: cardiovascular disease; dyslipidemia; diabetes; obesity; inflammation; oxidative stress; biomarkers; microRNA; extracellular vesicles; cardiopulmonary disease
Epstein-Barr Virus Disease Mechanisms and Stress Responses: 2nd Edition submission deadline 30 Nov 2024 | Viewed by 211 | Submission Open
Keywords: Epstein– Barr virus (EBV); reactivation; immune modulation; stress; aging
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Research on Chromosome Abnormalities and Genomic Disorders
edited by and Vijay S. Tonk
submission deadline 30 Nov 2024 | Viewed by 197 | Submission Open
Keywords: genomic testing; whole-exome sequencing; microarray analysis; cytogenetics; DNA diagnosis; DNA variation; DNA variant qualification; genetic disease
(This special issue belongs to the Section Molecular Genetics)
Immune Modulation and Atherosclerosis
edited by Xinjie Lu
submission deadline 30 Nov 2024 | Viewed by 191 | Submission Open
Keywords: atherosclerosis; cardiovascular disease; immune modulatory therapy; vaccinations
(This special issue belongs to the Section Molecular Medicine)
The Molecular and Pathophysiological Basis of Ectopic Fat Deposition in Non-adipose Tissues submission deadline 30 Nov 2024 | Viewed by 176 | Submission Open
Keywords: metabolic dysfunction-associated hepatosteatosis; myosteatosis; pancreatic steatosis; pancreatic adipocytes; visceral adipose tissue; cardiac steatosis; cardiac adipose tissue; kidney steatosis; macrophage steatosis; perirenal adipose tissue; lipophagy
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Sex and Evolution
edited by and
submission deadline 30 Nov 2024 | Viewed by 173 | Submission Open
Keywords: sex determination; sex chromosome evolution; reproduction; hybridization; speciation; evolution; animals; vertebrates
(This special issue belongs to the Section Molecular Genetics)
Molecular Mechanisms of Cardiovascular Remodeling
edited by
submission deadline 30 Nov 2024 | Viewed by 158 | Submission Open
Keywords: vascular remodeling aging; extracellular matrix; atherosclerosis peripheral; artery disease; chronic heart failure; cardiovascular associated cognitive decline
(This special issue belongs to the Section Molecular Biology)
Advances in Liver Transplantation and Hepatocellular Carcinoma
edited by
submission deadline 30 Nov 2024 | Viewed by 126 | Submission Open
Keywords: biomolecular markers of liver graft quality; the prediction role of biomolecular markers in liver transplantation; biomolecular markers of graft viability in the setting of machine perfusion technology; biomolecular markers of liver graft dysfunction; HCC biomarkers: AFP; PIVKA; and SPIK; the role of inflammation and immunity; standards of biomolecular HCC diagnosis; biomolecular-based diagnostic algorithms for HCC; biomolecular-based screening and prevention algorithms; advantages and pitfalls of existing biomolecular diagnosis
Recent Developments in Biohybrid Systems for Human Pluripotent Stem Cells and Beyond submission deadline 30 Nov 2024 | Viewed by 99 | Submission Open
Keywords: biohybrid systems; cell– material interaction; stem cells
(This special issue belongs to the Section Cellular Biochemistry)
Recent Advances in Anti-tumor Metal Complexes and Drug Delivery Systems: Second Edition
edited by Jasmina Dimitrić Marković, and
submission deadline 30 Nov 2024 | Viewed by 87 | Submission Open
Keywords: transition metal complexes; synthesis; structural characterization; biological activity; in silico methods; drug delivery
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