Recent Advances in Aptasensors for Clinical, Environmental and Food Safety Analysis
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Environmental Biosensors and Biosensing".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 2021
Special Issue Editors
2. Department of Pharmacy, University of Naples “Federico II”, Via Domenico Montesano, 49, 80131 Napoli, Itatly
Interests: impedimetric; electrochemicaluminescence-based and optical biosensors; characterization of ligand/biomolecule interactions; point-of-care tests; portable analytical devices
Interests: surface functionalization; electrochemical biosensors; assay development; new materials for biosensor development
Special Issues, Collections and Topics in MDPI journals
2. Centre for Applied Synthetic Biology, Concordia University, 7141 Sherbrooke St. West, Montreal, QC, Canada
Interests: electrochemical biosensors; point-of-care testing; microfluidic ‘lab-on-chip’ devices; nutrient recycling; water resource sustainability; water electrolysis
Special Issue Information
Dear Colleagues,
Aptamer-based biosensors have garnered considerable attention in recent years thanks to their potential as versatile and sensitive tools for the detection of a wide range of targets, including biomolecules, pathogens and chemicals. The core principle behind aptamer-based biosensors is the highly specific binding affinity between an aptamer and its target molecule. The use of biotechnology and nanotechnology has paved the way for the development of aptamers with specific molecular recognition ability, which can be used in fabricating various biosensors to provide highly sensitive and selective responses.
Compared to traditional biosensors that rely on enzymes or antibodies for target recognition, aptamer-based biosensors have several advantages. Firstly, aptamers can be obtained through an in vitro selection process called the systematic evolution of ligands by exponential enrichment (SELEX), which allows for high affinity and specificity towards target molecules. Moreover, aptamers can be engineered to have desired properties such as stability and selectivity by modifying their sequence or structure. Additionally, compared to antibody-based biosensors, aptamer-based biosensors offer higher productivity, as they can be easily synthesized in vitro. Overall, aptamer-based biosensors have emerged as a promising technology for various applications such as point-of-care testing, clinical diagnostics, food safety monitoring and environmental analysis. In this Special Issue, we aim to collect not only the many successful examples of aptasensors, but also studies that investigate the analytical limitations of such sensing platforms.
Dr. Giulia Moro
Dr. Rui Campos
Dr. László Kékedy-Nagy
Guest Editors
Manuscript Submission Information
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Keywords
- DNA
- RNA
- aptamer
- small molecule
- protein
- diagnostic
- prognostic
- biomarkers
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