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Biosensors
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Hydrogel Flexible Biological Electrode for Health Monitoring
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Hydrogel Flexible Biological Electrode for Health Monitoring

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 10255

Special Issue Editor

Prof. Dr. Jiaqi Lin

E-Mail Website
Guest Editor
School of Bioengineering, Dalian University of Technology, Dalian 116024, China
Interests: hydrogel flexible biological electrode

Special Issue Information

Dear Colleagues,

This Special Issue of Biosensors features original research on novel hydrogel, biomaterial, or conductive polymer-based flexible electrodes that can be applied in various health monitoring scenarios. Research focusing on the design, synthesis, and fabrication of the flexible conductive materials is encouraged. Research focusing on the electrode–skin interface, especially on reducing the skin-contacting resistance of the electrodes, is particularly welcome. Additionally, research focusing on in vitro and in vivo health monitoring and the biomedical applications of hydrogel electrodes is also welcome.      

Prof. Dr. Jiaqi Lin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogel electrodes
  • biomaterials
  • conductive polymer
  • electrode-skin interface
  • contacting resistance
  • health monitoring

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Published Papers (3 papers)

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Research

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14 pages, 2723 KiB  
Article
High-Performance Zwitterionic Organohydrogel Fiber in Bioelectronics for Monitoring Bioinformation
by Jun Xia, Jiabei Luo, Boya Chang, Chuanyue Sun, Kerui Li, Qinghong Zhang, Yaogang Li, Hongzhi Wang and Chengyi Hou
Biosensors 2023, 13(1), 115; https://doi.org/10.3390/bios13010115 - 9 Jan 2023
Cited by 1 | Viewed by 2344
Abstract
Bioinformation plays an imperative role in day-to-day life. Wearable bioelectronics are important for sensing bioinformation in real-time and conductive hydrogel fibers are a key component in next generation wearable bioelectronics. However, current conductive hydrogel fibers have remarkable disadvantages such as insufficient conductivity, stability, [...] Read more.
Bioinformation plays an imperative role in day-to-day life. Wearable bioelectronics are important for sensing bioinformation in real-time and conductive hydrogel fibers are a key component in next generation wearable bioelectronics. However, current conductive hydrogel fibers have remarkable disadvantages such as insufficient conductivity, stability, and bioinformation sensing ability. Here, we report the synthesis of a zwitterionic organohydrogel (ZOH) fiber by the combination of the mold method and solvent replacement strategy. The ZOH fiber shows transparency (92.1%), stretchability (905.8%), long-term stability, anti-freezing ability (−35–60 °C), and low light transmission loss (0.17 dB/cm). Then, we integrate the ZOH fiber into fabric for use as a bioinformation sensor, the results prove its capability as a bioinformation monitor, monitoring information such as motion and bioelectric signals. In addition, the potential of the ZOH fiber in optogenetic applications is also confirmed. Full article
(This article belongs to the Special Issue Hydrogel Flexible Biological Electrode for Health Monitoring)
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Review

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24 pages, 8625 KiB  
Review
Hydrogel Bioelectronics for Health Monitoring
by Xinyan Lyu, Yan Hu, Shuai Shi, Siyuan Wang, Haowen Li, Yuheng Wang and Kun Zhou
Biosensors 2023, 13(8), 815; https://doi.org/10.3390/bios13080815 - 14 Aug 2023
Cited by 8 | Viewed by 3284
Abstract
Hydrogels are considered an ideal platform for personalized healthcare due to their unique characteristics, such as their outstanding softness, appealing biocompatibility, excellent mechanical properties, etc. Owing to the high similarity between hydrogels and biological tissues, hydrogels have emerged as a promising material candidate [...] Read more.
Hydrogels are considered an ideal platform for personalized healthcare due to their unique characteristics, such as their outstanding softness, appealing biocompatibility, excellent mechanical properties, etc. Owing to the high similarity between hydrogels and biological tissues, hydrogels have emerged as a promising material candidate for next generation bioelectronic interfaces. In this review, we discuss (i) the introduction of hydrogel and its traditional applications, (ii) the work principles of hydrogel in bioelectronics, (iii) the recent advances in hydrogel bioelectronics for health monitoring, and (iv) the outlook for future hydrogel bioelectronics’ development. Full article
(This article belongs to the Special Issue Hydrogel Flexible Biological Electrode for Health Monitoring)
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28 pages, 12805 KiB  
Review
Hydrogel-Based Bioelectronics and Their Applications in Health Monitoring
by Jiangbo Hua, Mengrui Su, Xidi Sun, Jiean Li, Yuqiong Sun, Hao Qiu, Yi Shi and Lijia Pan
Biosensors 2023, 13(7), 696; https://doi.org/10.3390/bios13070696 - 30 Jun 2023
Cited by 14 | Viewed by 4100
Abstract
Flexible bioelectronics exhibit promising potential for health monitoring, owing to their soft and stretchable nature. However, the simultaneous improvement of mechanical properties, biocompatibility, and signal-to-noise ratio of these devices for health monitoring poses a significant challenge. Hydrogels, with their loose three-dimensional network structure [...] Read more.
Flexible bioelectronics exhibit promising potential for health monitoring, owing to their soft and stretchable nature. However, the simultaneous improvement of mechanical properties, biocompatibility, and signal-to-noise ratio of these devices for health monitoring poses a significant challenge. Hydrogels, with their loose three-dimensional network structure that encapsulates massive amounts of water, are a potential solution. Through the incorporation of polymers or conductive fillers into the hydrogel and special preparation methods, hydrogels can achieve a unification of excellent properties such as mechanical properties, self-healing, adhesion, and biocompatibility, making them a hot material for health monitoring bioelectronics. Currently, hydrogel-based bioelectronics can be used to fabricate flexible bioelectronics for motion, bioelectric, and biomolecular acquisition for human health monitoring and further clinical applications. This review focuses on materials, devices, and applications for hydrogel-based bioelectronics. The main material properties and research advances of hydrogels for health monitoring bioelectronics are summarized firstly. Then, we provide a focused discussion on hydrogel-based bioelectronics for health monitoring, which are classified as skin-attachable, implantable, or semi-implantable depending on the depth of penetration and the location of the device. Finally, future challenges and opportunities of hydrogel-based bioelectronics for health monitoring are envisioned. Full article
(This article belongs to the Special Issue Hydrogel Flexible Biological Electrode for Health Monitoring)
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