Application of Surgery in Epilepsy

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurosurgery and Neuroanatomy".

Deadline for manuscript submissions: 15 January 2025 | Viewed by 59

Special Issue Editors


E-Mail Website
Guest Editor
1. Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
2. Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Interests: neurosurgery; epilepsy; brain tumor; movement disorders; spasticity

E-Mail Website
Guest Editor
Doctor of Medicine, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: epilepsy surgery; pediatrics; ECoG signal processing

Special Issue Information

Dear Colleagues,

The surgical management of epilepsy is an ever-broadening field with intense controversies and new treatments that are already both commonplace and being utilized with widely different strategies from institution to institution. In this Special Issue, we aim to amplify recent developments in these treatments, insights from clinical experience, translational or relevant basic science research, or thorough reviews not recently covered elsewhere.

A large proportion of patients with drug-resistant epilepsy have multifocal, generalized, eloquent-onset, or broad onset epilepsy, and are poor candidates for traditional resective surgery. Beyond a ketogenic diet and vagus nerve stimulation, intracranial neuromodulation had demonstrated great promise and has become a rapidly growing field unto itself. Although early studies demonstrated the proof of principle that it is often effective, a wide range of stimulation strategies, targets, stimulation parameters, and technical nuances are currently being explored individually by many institutions. We encourage these strategies to be reported here.

The lessons learned from using temporarily or permanently implanted electrodes can give us remarkable insights into both epilepsy and cognition, and with the vast number of such electrodes implanted every day, we continue to be fascinated by these research experiences.

Reports on outcomes from all types of epilepsy surgery are similarly encouraged for submission to this Special Issue.

Sincerely,

Dr. Benjamin C. Kennedy
Dr. Samuel Tomlinson
Guest Editors

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Keywords

  • epilepsy surgery
  • neuromodulation
  • drug-resistant epilepsy
  • sEEG
  • DBS
  • RNS
  • LITT

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