HIV-Associated Neurological Diseases
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropharmacology and Neuropathology".
Deadline for manuscript submissions: 15 April 2025 | Viewed by 40
Special Issue Editor
Special Issue Information
Dear Colleagues,
Background and history of this topic: Effective antiretroviral (ARV) treatment has resulted in a global increase in life expectancy for people living with HIV, and in Western countries, approximately 40% of PLWH are over the age of 50. The aging process in people with HIV is complex due to the interaction between the virus, long-term antiretroviral therapy (ART), and aging itself. Aging PLWH are at particular risk of cerebrovascular disease through various mechanisms, including chronic inflammation, immune dysregulation, antiretroviral medications, and the direct effects of the virus on the vascular endothelium.
Aim and scope of this Special Issue: We aim to explore the complex relationships between cerebrovascular health and HIV infection. In this Special Issue, we will highlight the increased risk and unique challenges faced by aging individuals living with HIV. It is essential that we understand how chronic HIV infection and long-term ART impact cerebrovascular health and contribute to conditions such as stroke, transient ischemic attacks (TIAs), and vascular cognitive impairment.
Cutting-edge research: The latest research on the cerebrovascular health of HIV-positive individuals is revealing important insights into how chronic HIV infection and long-term antiretroviral therapy (ART) impact vascular health via genetics, neuroimaging biomarkers, clinical manifestations, and lifestyle and behavioral interventions.
What kind of papers we are soliciting: We invite original research articles, reviews, case studies, and clinic trials that provide insights into the cerebrovascular health of aging PLWH. The following topics are of particular interest:
- Pathophysiology and mechanisms;
- Epidemiology and risk factors;
- Clinical manifestations and outcomes;
- Considerations of cerebrovascular health in diverse populations;
- Biomarkers of cerebrovascular health;
- Therapeutic interventions and management.
Prof. Dr. April Thames
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- HIV
- aging
- cerebrovascular disease
- cultural factors
- lifetime stress
