The Role of the STN in Inhibition of Action and Uncertainty Monitoring
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (30 August 2020) | Viewed by 285
Special Issue Editors
Interests: movement disorders; Parkinson´s disease; cognitive neurology and neuromodulation techniques; deep brain stimulation; motor cortex stimulation; non-invasive methods as tDCS, tACS, tRNS and (r)TMS and neurofeedback
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Special Issue Information
Dear Colleagues,
The subthalamic nucleus (STN) is an interesting structure of the brain, both from a basic neuroscience and therapeutic point of view. Deep brain stimulation (DBS) of the motor STN is an invasive neuromodulation technique for the treatment of motor dysfunctions in Parkinson‘s disease (PD). However, nonmotor functions of the STN have gained interest in the recent years. Nonmotor STN networks could explain cognitive and emotional side effects in DBS in PD as well as beneficial effects of STN–DBS in psychiatric diseases such as obsessive–compulsive disorder (OCD). The STN, which appears to be a key structure of the basal ganglia shown to rapidly modulate the functioning of the corticobasal ganglia circuitry, seems to play a role in executive functions, motor control, and metacognition.
Specifically, in OCD, two mechanisms are discussed to be of interest for the role of the STN: action inhibition and uncertainty monitoring.
We invite researchers from different fields to submit their original work or reviews to this Special Issue: from basic animal or human neuroscience, imaging, electrophysiology, behavioral science, and clinical neuroscience.
Dr. Lars Wojtecki
Dr. Luc Mallet
Guest Editors
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Keywords
- Subthalamic nucleus
- Inhibition of action
- Uncertainty monitoring
- Parkinson’s disease
- Obsessive–ompulsive disorder
- Neurophysiology
- Deep brain stimulation
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