The Role of Epstein–Barr Virus in Human Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Infectious Agents and Cancer".
Deadline for manuscript submissions: 15 September 2025 | Viewed by 60
Special Issue Editors
2. Department of Medical Biotechnology, Università degli Studi di Siena, Siena, Italy
Interests: EBV; lymphoma; cancer biology; EBV-related malignancies; immune response; tumour microenvironment
Special Issues, Collections and Topics in MDPI journals
Interests: lung cancer; EBV; cancer; EBV-related disorders; tumour microenvironment; lymphomagenesis; immune response
Special Issue Information
Dear Colleagues,
More than 90% of the world’s population is infected with the Epstein–Barr virus (EBV), an oncogenic virus aetiologically linked to autoimmune conditions (e.g., multiple sclerosis, rheumatoid arthritis, and lupus), two pre-malignant lymphoproliferative diseases (LPDs), and up to nine distinct human tumours including hematologic malignancies (e.g., diffuse large B-cell lymphoma (DLBCL), Hodgkin lymphoma (HL), Burkitt lymphoma (BL)), and epithelial cancers (e.g., nasopharyngeal carcinoma and gastric cancer).
Since its discovery in 1964, evidence indicates that various EBV-encoded proteins, including non-coding RNAs, contribute to developing EBV-associated cancers. Despite more than 60 years of research on EBV, we still lack complete knowledge of the natural history of EBV infection and how the virus interacts with different risk factors to drive the development of cancer.
This Special Issue aims to provide an up-to-date assessment of the current status of our understanding of EBV’s contribution to virus-associated malignancies and how this knowledge impacts the diagnosis and treatment of these cancers.
To advance the understanding of EBV-related cancers, we welcome the submission of original research and reviews addressing different aspects of EBV infection.
We look forward to receiving your contributions.
Dr. Lucia Mundo
Dr. Cristiana Bellan
Dr. Stefano Lazzi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Epstein–Barr virus
- cancer
- EBV-driven malignancies
- tumour microenvironment
- immune response
- immunotherapy
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