Merkel Cell Carcinoma: From Molecular Mechanisms to Clinical Therapy—a Selection of Papers from the 8th Nordic/1st European MCC Meeting

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 50

Special Issue Editors


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Guest Editor
1. Department of Dermatology, Translational Skin Cancer Research, German Cancer Consortium (DKTK) Partner Site Essen/Düsseldorf, University Duisburg-Essen, 47057 Essen, Germany
2. Translational Skin Cancer Research, DKTK Site Essen, ED03, Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany
Interests: skin cancer; tumor biology; tumor immunology; tumor evolution; biomarker; clinical trials; epidemiology
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Guest Editor
Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany
Interests: virology; viral carcinogenesis; molecular biology; skin cancer

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Guest Editor
Department of Dermatology and Venereology, University of Gothenburg, Gothenburg, Sweden
Interests: skin cancer; clinical trials; dermoscopy; dermatologic surgical procedures

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Guest Editor
Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden
Interests: skin cancer; molecular biology; viral carcinogenesis; tumor immunology; biomarker
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite you to contribute to a Special Issue focused on Merkel cell carcinoma (MCC), a rare but highly informative skin cancer that offers unique insights into tumor biology and immunology. MCC's distinct characteristics make it an ideal subject for research aimed at translating scientific discoveries into clinical applications to enhance cancer care.

MCC presents two primary etiologies—virus-associated and UV-associated—both of which render the tumor highly immunogenic. This dual nature not only allows researchers to investigate the underlying carcinogenic mechanisms of this disease but also to explore its immunological responses, both spontaneous and therapeutically induced.

The MCC research community is known for its collaborative spirit, as demonstrated by the 8th Nordic/1st European MCC Meeting, where experts from around the globe gathered to share the latest findings in MCC molecular biology, immunology (including the impact of the tumor microenvironment), biomarkers, epidemiology, early diagnosis, current therapies, and clinical trials. This gathering also provided an opportunity to strategize on future directions in the fight against MCC and other cancers.

This Special Issue will compile papers on both basic and clinical research presented at the 8th Nordic/1st European MCC Meeting. We welcome submissions that advance our understanding of MCC and contribute to the broader field of cancer research.

Researchers are encouraged to submit their findings as either original articles, reviews, or brief communications.

Prof. Dr. Jürgen C. Becker
Prof. Dr. Nicole Fischer
Dr. John Paoli
Dr. Weng-Onn Lui
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • merkel cell carcinoma
  • molecular biology
  • virology
  • immunology
  • biomarkers
  • epidemiology
  • primary treatment (surgery, radiation therapy)
  • immunotherapy
  • targeted therapy
  • clinical trials

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Published Papers

This special issue is now open for submission.
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