Omics Data for Cancer Therapies: From Molecular Profiling to Clinical Applications
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Informatics and Big Data".
Deadline for manuscript submissions: 31 October 2026
Special Issue Editor
2. Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland
Interests: bioinformatics; biostatistics; non-coding RNAs; lymphoma; high-throughput sequencing data analysis; diagnostic and prognostic biomarkers discovery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The rapid advancement of high-throughput omics technologies—including genomics, transcriptomics, epigenomics, proteomics, and metabolomics—has significantly reshaped our understanding of cancer biology. These data-rich approaches are instrumental in identifying biomarkers, elucidating mechanisms of resistance, uncovering novel therapeutic targets, and supporting the development of precision oncology. This Special Issue will bring together original research articles and comprehensive reviews that leverage omics data to advance cancer therapies. We invite submissions that explore integrative analyses, the data-driven discovery of therapeutic vulnerabilities, biomarker identification, personalized treatment strategies, and the translational potential of multi-omics data. We particularly encourage studies that utilize publicly available or large-scale clinical datasets, apply innovative computational approaches, or address the challenges of integrating omics data into clinical decision-making.
Topics of interest include, but are not limited to, the following:
- Multi-omics approaches in cancer therapy development;
- Integrative omics for biomarker discovery and validation;
- Omics-driven patient stratification and personalized treatment;
- Tumor heterogeneity and microenvironment characterization through omics;
- Longitudinal and spatial omics data in treatment monitoring;
- Predictive modeling and machine learning applied to cancer omics;
- Omics approaches to drug repurposing and resistance mechanisms;
- Translational studies bridging omics data and clinical outcomes.
Dr. Luciano Cascione
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- multi-omics integration
- precision oncology
- biomarker discovery
- computational oncology
- translational cancer research
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