Molecular PET Imaging in Cancer Metabolic Studies
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 47
Special Issue Editors
Interests: cancer metabolism; immunological PET; imaging of infectious diseases
Special Issues, Collections and Topics in MDPI journals
Interests: PET tracers; radiosynthesis; PET imaging; cancer; pharmacodynamics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Positron Emission Tomography (PET) is a highly sensitive, non-invasive imaging modality that can precisely detect/trace molecular-level targets or processes in the whole body using suitable radiotracers. PET has demonstrated significant value in cancer diagnosis and tumor metabolism and is now a critical component of oncologic clinical management as well as translational cancer research. Integrating PET with other anatomical imaging modalities such as MRI or CT can provide more comprehensive insights into tumor microenvironment and cancer metabolism by combining PET derived functional information at the molecular level with MRI or CT derived anatomical detail. PET imaging with metabolic tracers like 18F-fludeoxyglucose (18F-FDG, glucose analog) has been extensively utilized clinically to detect varied cancers based on upregulated glucose metabolism (a phenomenon known as the Warburg effect). However, 18F-FDG PET has challenges with false positives from high metabolic activity in non-malignant conditions, and false negatives with non-glucose avid tumors. This has necessitated expansion of novel PET agent development beyond traditional glycolysis imaging processes to delineate other novel physiological markers or pathways driving cancer progression. This issue will incorporate articles identifying new PET imaging agents targeting such physiological pathways governing varied aspects of tumor biology including imaging of upregulated oncogenic proteins or receptors and cancer neoantigens.
Dr. Aditi Mulgaonkar
Dr. Sashi Debnath
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- PET imaging
- PET/CT
- PET/MRI
- cancer metabolism
- tumor microenvironment
- cancer antigens
- radiotracers
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