Management of Recurrent Endometrial Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 147

Special Issue Editors


E-Mail Website
Guest Editor
1. Academic Department of Gynaecological Oncology, Royal Surrey NHS Foundation Trust, Surrey, Guildford GU2 7XX, UK
2. Brunel Department of Life Sciences, Brunel University London, Kingston Lane Uxbridge, Middlesex, Uxbridge UB8 3PH, UK
Interests: endometrial cancer; gynecological cancer

E-Mail Website
Guest Editor
Consultant Clinical Oncologist, Royal Surrey Foundation Trust Hospital, Guildford, UK
Interests: gynecological cancer; lower gastrointestinal cancer; high-dose-rate brachytherapy

E-Mail Website
Guest Editor
Consultant Gynae-Oncology Surgeon, Royal Surrey Foundation Trust Hospital, Guildford, UK
Interests: general gynecology, including menstrual disorders, pelvic pain, fibroids, and menopause; endometriosis; abnormal smears and colposcopy; gynecological cancers (cervical, ovarian, endometrial, vulval, and vaginal); robotic surgery

Special Issue Information

Dear Colleagues,

The incidence of endometrial cancer is rising globally at an alarming rate. Worldwide, mortality from endometrial cancer has increased significantly over the last two decades. In the USA, a 21% increase has been seen. With rising obesity, endometrial cancer is a health problem for women globally. There is an increasing trend towards seeing younger women present with endometrial cancer for what was once described as a cancer of elderly post-menopausal women. Approximately 15–20% of all patients diagnosed with endometrial cancer will recur after primary treatment, and most of this recurrence unfortunately happens in the first 2–3 years after initial diagnosis. Treatment for recurrent endometrial cancer varies between local, systemic, or surgical treatment. Current molecular stratification has shown an impact on prognosis for endometrial cancer. Appropriate staging for endometrial cancer at primary surgery dictates the need for appropriate adjuvant treatment. There continues to be considerable variation in the approach to treating advanced endometrial cancer. There is also variation in the approach to treating recurrent endometrial cancer depending on the availability of expertise at the treatment center. Further research is required to fully understand the role of molecular stratification in streamlining treatment in the recurrent setting. A more homogenous and uniform approach to treating recurrent endometrial cancer is an urgent need for the global gynae-oncology community. Novel molecular markers may play an important role in predicting recurrence by risk stratification and by identifying possibilities of initial treatment failure. 

Original research articles and reviews are welcome to be submitted to this Special Issue. 

Prof. Dr. Jayanta Chatterjee
Dr. Alexandra Stewart
Dr. Hersha Patel
Prof. Dr. Emmanouil Karteris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • recurrence patterns
  • molecular markers
  • staging
  • risk prediction
  • treatment failure
  • mortality from endometrial cancer

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers

This special issue is now open for submission.
Back to TopTop