Endoscopic Ultrasound Fine-Needle Biopsy of Gastrointestinal Tumors

Dear Colleagues,

The development of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) needles has generated a great deal of interest in the field of EUS tissue acquisition (TA), primarily based on proposed advantages over EUS fine-needle aspiration (FNA) needles concerning diagnostic accuracy. Furthermore, EUS-FNB seems to improve procurement of samples with preserved tissue architecture, thus allowing for immunohistochemistry required for certain diagnoses, obviating the need for an on-site pathologist and obtaining results in fewer passes.

Several recent meta-analyses and trials have suggested a clear superiority of EUS-FNB over EUS-FNA both in pancreatic masses and subepithelial lesions. However, further data are needed particularly in light of newer FNB needles that were recently introduced in endoscopic practice, such as fork-tip and franseen needles.

In this Special Issue, we will publish reviews and original research that provide new insights into the role of EUS-guided fine-needle biopsy in gastrointestinal tumors.

Dr. Antonio Facciorusso
Guest Editor

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• EUS
• FNB
• Tissue acquisition
• Accuracy
• Sensitivity
• Specificity
• Cancer