Synaptic Plasticity in Brain and Nerves: New Vistas in Health and Diseases (2nd Edition)

Dear Colleagues,

The efficiency of brain-dependent functions is closely related to optimal communication within neuronal networks, which is finely regulated by a myriad of adaptative processes involving interactions between the nerve and glial cell elements of the synaptic cleft. The capacity of brain plasticity that manages the network adaptation to environmental changes ranges from short-term modifications of cell morphology and functionality to long-term homeostatic responses. This new edition of Special Issue aims to showcase original articles and reviews that will improve our current knowledge on the cellular and molecular mechanisms underlying Hebbian and homeostatic forms of synaptic plasticity. The exact nature of cellular interactions and the associated signaling pathways that contribute to the modulation of synaptic strength in cerebral networks, as well as an assessment of whether these processes are ubiquitous or show region specificity in the healthy brain, remain a current topic of major interest. In addition, we welcome all articles that consider if specific alterations of synaptic adaptative processes are indicative of selective brain-related disorders that could help to initiate new preventive strategies.

Dr. Jean-Marie Billard
Guest Editor

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