Cellular and Molecular Mechanisms in Oxidative Stress-Related Chronic Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 783
Special Issue Editors
Interests: cell physiology; membrane transport systems; bioactive compounds; oxidative stress; aging human health
Interests: human physiology; cell physiology; membrane transport systems; bioactive compound; oxidative stress; human health
Special Issues, Collections and Topics in MDPI journals
Interests: physiology; ion trasport; band 3 protein; erythrocytes; oxidative stress; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress is frequently described as the balance between the production of reactive species in biological systems and the ability of the latter to defend through sophisticated antioxidant machinery. Nevertheless, when oxidants are produced in excess or when the antioxidant defenses that regulate them are ineffective, this balance can be perturbed, thus resulting in an oxidative condition. Oxidative products are highly reactive and can directly or indirectly modulate the cellular functions through complex signaling cascades. In this regard, the magnitude and exposure of the insult, as well as the cell type involved, are key elements in defining which pathways are activated, as well as the final cell outcome. The aim of this Special Issue is to collect and contribute to the dissemination of high-quality research articles as well as review articles, focusing on cell responses to oxidative stress in different pathologic conditions, mainly those displaying systemic oxidative stress as a hallmark. To this aim, possible mechanisms of cell adaptation and the potential beneficial effects of antioxidants in the context of redox imbalance will be worthy of note. Studies using animal or cell models are welcome.
Dr. Sara Spinelli
Dr. Alessia Remigante
Dr. Rossana Morabito
Guest Editors
Manuscript Submission Information
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Keywords
- aging
- age-related diseases
- redox system
- cellular and molecular mechanisms
- oxidative stress biomarkers
- synthetic and natural antioxidant molecules
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