Novel Insights into Molecular Mechanisms of Iron-Related Skin Damage and Disorders
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 6905
Special Issue Editors
Interests: skin photoprotection; skin ironome; iron chelation therapy; photodynamic therapy of skin disorders; oxidative stress; iron sensors
Special Issues, Collections and Topics in MDPI journals
Interests: thioredoxin; selenium; thiol; drug target; inflammation; nonalcoholic fatty liver disease; inflammatory bowel disease; cancer; antibacterial agent
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Interests: skin organoid formation; stem cells; wound healing; dermatology; hair follicles; regenerative medicine.
Special Issues, Collections and Topics in MDPI journals
Interests: skin photoaging; autophagy; dermatology; photobiology; photomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This issue will look at the interplay between iron and oxidative stress in skin pathologies as well as skin damage due to exposure to environmental exposomes, notably sunlight. At cellular level, the phenomenon of iron-mediated cell death (ferroptosis) has also been linked to evasion or initiation and promotion of various pathologies. In all these cases, the use of iron chelators or compounds with iron-binding activity in conjunction with antioxidants appears to be beneficial as a preventive or therapeutic approach against iron-mediated oxidative damage and pathologies. There is now a clear need to understand these phenomena within the context of sunlight-mediated disruption of iron and redox homeostasis and initiation and promotion of skin inflammatory and hyperproliferative disorders. This specific issue will therefore welcome research articles and reviews discussing and reporting on basic skin research as well as preclinical and clinical dermatology-based studies within the context of iron, oxidative stress, and pathologies.
Prof. Dr. Charareh Pourzand
Prof. Dr. Jun Lu
Prof. Dr. Mingxing Lei
Prof. Dr. Julia Li Zhong
Guest Editors
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Keywords
- iron
- reactive oxygen species
- skin
- exposomes
- sun damage
- sun protection
- dermatology
- skin disorders
- skin cancer
- skin inflammatory disorders
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