Molecular and Cellular Mechanisms of Brain Development and Neurodevelopmental Disorders
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 November 2025 | Viewed by 5
Special Issue Editor
Interests: epigenetics; DNA methylation; transcriptional control; gene regulation; drug repurposing; neural stem cells; neurodevelopmental disorders; medulloblastoma brain tumor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Collogues,
Brain development is a complex process that is highly regulated at different cellular and molecular levels. Accordingly, specific regulatory mechanisms are in place to ensure the proper expression of key developmental genes. During development, a population of neuronal progenitor cells known as neural stem cells build the central nervous system through differentiating into specific cell types. These progenitor cells represent fundamental biological systems that can be used to study the mechanisms of cell fate determination in the developing and adult brain. Such systems could include in vitro and in vivo models, benefiting from classical and novel technologies.
This Special Issue welcomes review articles and original research studies that cover relevant research in model systems that investigate different molecular and cellular mechanisms of brain development and their impact in neurodevelopmental disorders. We encourage submissions in different areas of research and disciplines, including embryonic brain development and adult brain function and physiology, the epigenetic basis of brain cell development and their deregulation in neurodevelopmental diseases, cell signaling pathways in brain cells, neural stem cell differentiation and self-renewal, gene regulatory mechanisms in relevant model systems, the molecular and cellular basis of brain diseases, next-generation sequencing and multi-omics studies, and neuroscience.
Prof. Dr. Mojgan Rastegar
Guest Editor
Manuscript Submission Information
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Keywords
- brain development
- neural stem cells
- neurodevelopmental disorders
- brain diseases
- cellular and molecular mechanisms
- embryonic and adult brain
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