Stem Cells in Organoid Technology
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: closed (15 April 2023) | Viewed by 6763
Special Issue Editor
Special Issue Information
Dear Colleagues,
Stem cells can be divided into two main forms: pluripotent stem cells, including embryonic stem cells, and induced pluripotent stem cells, which can differentiate into any cell in the body. Adult stem cells are multipotent, which means they can only change into some cells in the body, not any cell. Their unique characteristics to differentiate into other cell types (pluripotency) allow us to use stem cells as valuable tools for research and therapeutic applications. During the past few decades, stem cell differentiation technology has made remarkable progress. Additionally, organoid technology has recently been developed. Organoids are three-dimensional cell structures grown in vitro from stem cells, primarily isolated from biopsies or pluripotent stem cells, which recapitulate key features of native organs from a histological and functional perspective. Organoids can be widely utilized for various purposes, such as organ development, disease modeling, drug development, regenerative medicine, etc.
This Special Issue of Cells will focus on the development of innovative technologies in the generation of pluripotent stem-cell-derived organoids and their application in disease modeling, as well as regenerative medicine.
Dr. Min Young Lee
Guest Editor
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Keywords
- pluripotent stem cells
- cerebral organoid
- midbrain organoid
- Alzheimer’s disease
- Parkinson’s disease
- cardiac differentiation
- neural differentiation
- tissue repair
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