Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Microenvironment".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 110

Special Issue Editors


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Guest Editor
Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada
Interests: cancer invasion and metastasis; receptor tyrosine kinases; animal models of cancer; comparative oncology; cancer biomarker discovery

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Guest Editor
Laboratory Medicine, Department of Pathology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada
Interests: cancer cell biology; tumor biology; signal transduction; receptors; xenografts; tumor-initiating cells

Special Issue Information

Dear Colleagues,

This Special Issue, entitled "Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy," aims to explore the intricate dynamics of the tumor microenvironment (TME) and the signaling pathways that drive cancer progression. By focusing on the TME, this Special Issue will delve into how various components, such as immune cells, stromal cells, and the extracellular matrix, interact with cancer cells to influence tumor behavior and response to treatments. Additionally, it will highlight the significance of signaling pathways in tumor development and metastasis, presenting novel insights into their potential as therapeutic targets. Our goal is to present cutting-edge research and innovative approaches that leverage the TME and signaling pathways to develop precision therapies tailored to individual patients. This Special Issue will include contributions from leading researchers and clinicians, covering topics such as the role of the TME in immune evasion, the impact of metabolic pathways on tumor growth, and the latest advancements in targeting key signaling molecules for improved therapeutic outcomes. Through a comprehensive examination of these areas, this Special Issue aims to pave the way for more effective and personalized cancer treatment strategies.

Dr. Behzad M. Toosi
Dr. Andrew Freywald
Guest Editors

Manuscript Submission Information

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Keywords

  • tumor microenvironment (TME)
  • signaling pathways
  • precision cancer therapy
  • immune evasion
  • metabolic pathways
  • tumor–stroma interactions
  • therapeutic targets
  • personalized medicine
  • cancer metastasis
  • molecular oncology

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Published Papers

This special issue is now open for submission.
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