Inter-organ Crosstalk in Energy Homeostasis
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 8555
Special Issue Editors
Interests: obesity; diabetes; gut–brain axis
Interests: metabolism; neuroscience; gut-brain axis; obesity and diabetes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic disorders, including diabetes and obesity, are on the rise in modern societies despite research efforts to tackle what is now considered a pandemic. Energy homeostasis involves a wide range of mechanisms, tissues and organs. Interestingly, all these partners are interacting with each other to maintain energy balance in physiological conditions. The central nervous system plays a key role by being strongly involved in the coordination of all these mechanisms. The brain constantly receives various signals (nutrients, metabolites, hormones, neural inputs, etc.) from peripheral organs (gut, liver, pancreas, adipose tissue, etc.), providing information on the body energy status. In addition to the brain, the peripheral organs can also sense multiple circulating cues, neural cues, or both, which ultimately leads to metabolic adaptations. This complex communication is crucial: considerable evidence of disrupted crosstalk has been reported between the brain and the periphery, but also between peripheral organs themselves in the development and maintenance of metabolic diseases. Therefore, a harmonious inter-organ collaboration is determinant for maintaining energy balance.
In this Special Issue we aim to bring together a collection of recent data exploring the complex relationships between the central nervous system and peripheral organs for energy homeostasis regulation. Specific areas of interest include but are not limited to nutrient sensing, gut–brain axis, brain–periphery communication, inter-organ communication, obesity, diabetes and nutrition.
Prof. Dr. Claude Knauf
Dr. Lionel Carneiro
Dr. Camille Allard
Guest Editors
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Keywords
- energy homeostasis
- brain–periphery
- obesity
- diabetes
- nutrition
- endocrinology
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