A Purview on Hippocampal Cells in Health and Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (10 September 2024) | Viewed by 1767
Special Issue Editors
Interests: neuroscience; biochemistry; molecular biology; bioinformatics and computational biology; cell signaling; cell culture; neurobiology; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals
Interests: glial neurobiology; animal cognition and behavior; neuroinflammation; neurodegeneration; brain cancer; neurodevelopment; neurodegenerative diseases; metabolic disease; neurotransmission; developing brain disorders
Special Issue Information
Dear Colleagues,
The hippocampus is the site of learning and memory, and as an essential part of the limbic system, it regulates cognitive and emotional behavior. During brain development, the hippocampus is the critical region for cell genesis and development. In adulthood, along with SVZ, it serves as a key ground for adult neurogenesis and maintains a healthy brain cell population. Various theories have favored the involvement of hippocampal cells in responses to spatial and non-spatial information unconventionally processed using a spatial framework, extending the perspective of hippocampal functions to the brain’s health and neurological disorders. With increasing age, the hippocampal cells’ plasticity and renewal ability increase their vulnerability, making the hippocampus a leading location for the commencement of various psychiatric and neurological disorders. Advancements in techniques like electrophysiology, neuropharmacology, single-cell sequencing, and histochemical characterization have made it easier to understand the hippocampus’ architecture and functions in more detail. This Special Issue will compile recent evidence and information regarding hippocampal cells at all stages of life during health and disease. Such information will not only enhance our understanding of the hippocampus but also allow us to utilize the hippocampal cells and pathways to treat several neurological disorders.
Dr. Dasiel O. Borroto Escuela
Dr. Aarti Nagayach
Guest Editors
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Keywords
- hippocampal cell physiology
- microglia
- astroglia
- neurodegenerative diseases
- neurogenesis
- action potential
- neuropharmacology
- neurotransmission
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