Hematopoiesis and Stem Cells

Dear Colleagues,

Since the pioneering studies of McCulloch and Till that marked the beginning of modern experimental hematology, over five decades of extensive research have yielded a tremendous wealth of information about the biology of the hematopoietic stem cell (HSC) compartment and the molecular mechanisms that govern its development and homeostasis, and have led to clinical applications of HSCs in the treatment of a variety of congenital and acquired disorders of the hematopoietic system. However, several aspects of HSC biology remain only partially understood, or controversial. This Special Issue of Cells aims to collect qualified contributions to shed additional light on our understanding of these cells. Therefore, we invite you to submit original research articles or reviews in all areas of HSC research, in particular focused on topics including, but not limited to:

• HSC heterogeneity
• Interactions between HSCs and the microenvironment in development, adult life and malignancies
• Influence of metabolism on HSC fate choice
• Epigenetic regulation of normal and malignant HSCs
• Stem cells in hematopoietic malignancies: biologic features and targeting strategies

Prof. Giovanni Morrone
Dr. Heather M. Bond
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.